SCHEMBL25626565

SCHEMBL25626565

CCOC(=O)C(CCC(CC(Br)C(=O)OC)C(=O)OCC)CC(Br)C(=O)OC

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ZDHHC7 Q9NXF8 1/20 0.49
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CPB2 Q96IY4 2/20 0.37
MGAM O43451 1/20 0.35
GAA P10253 1/20 0.35
SI P14410 1/20 0.35
MGAM2 Q2M2H8 1/20 0.35
KMT2A Q03164 3/20 0.34
MEN1 O00255 1/20 0.34
NPC1 O15118 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
ALDH1A1 P00352 3/20 0.33
TRPA1 O75762 1/20 0.33
POLB P06746 1/20 0.33
LMNA P02545 1/20 0.32
HSD17B10 Q99714 1/20 0.32
ALOX15 P16050 1/20 0.31
METAP2 P50579 1/20 0.31
METAP1 P53582 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25626564 0.90 CPB2 (0.40) ZDHHC7CPB2MGAMGAASI
SCHEMBL25626568 0.80 ALDH1A1 (0.40) ZDHHC7CA1CA2CPB2KMT2A
SCHEMBL16638165 0.79 ZDHHC7 (0.50) ZDHHC7CA1CA2KMT2A
SCHEMBL1415280 0.77 ZDHHC7 (0.54) ZDHHC7CA1CA2MGAMGAA
SCHEMBL24169913 0.77 ALDH1A1 (0.40) ZDHHC7CPB2MGAMGAASI
SCHEMBL1286734 0.75 ALDH1A1 (0.46) ZDHHC7MGAMGAASIMGAM2
SCHEMBL14016338 0.75 ALDH1A1 (0.46) ZDHHC7MGAMGAASIMGAM2
SCHEMBL25626563 0.75 TDP1 (0.47) KMT2AMEN1NPC1L3MBTL1ALDH1A1
SCHEMBL25626562 0.74 HSD17B10 (0.48) CA1CA2KMT2AMEN1NPC1
SCHEMBL12793990 0.73 ZDHHC7 (0.52) ZDHHC7CA1CA2KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11667790-B2 Polymer having reactive silicon-containing group and production method therefor SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-06-06 US disclosed