Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.37 |
| ▸ | PDE4A | P27815 | 2/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2560821 | 1.00 | HPGD (0.41) | HPGDSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL7709222 | 0.91 | SMN1; SMN2 (0.41) | HPGDSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL2562733 | 0.88 | KDM4E (0.39) | HPGDSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL2562731 | 0.88 | KDM4E (0.39) | HPGDSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL2556731 | 0.86 | CCNC (0.42) | HPGDSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL7707992 | 0.86 | PDE4B (0.43) | HPGDSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL2559970 | 0.83 | IDO1 (0.39) | LMNAMAPTCYP1A1CYP1A2CYP1B1 | |
| SCHEMBL2562005 | 0.78 | CCNC (0.42) | CYP1A1CYP1A2CYP2D6CYP1B1CYP3A4 | |
| SCHEMBL2562008 | 0.78 | CCNC (0.42) | CYP1A1CYP1A2CYP2D6CYP1B1CYP3A4 | |
| SCHEMBL2563005 | 0.78 | CCNC (0.42) | HPGDSMN1; SMN2MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011132051-A2 | TRICYCLE COMPOUNDS AS PHOSPHODIESTERASE-10 INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2011-10-27 | — | — | WO | disclosed |