Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25630826 | 0.84 | JAK3 (0.37) | ALDH1A1HPGDCYP3A4HSD17B10USP2 | |
| SCHEMBL30456080 | 0.83 | ALDH1A1 (0.54) | ALDH1A1HPGDCYP3A4HSD17B10USP2 | |
| SCHEMBL25269396 | 0.83 | ALDH1A1 (0.54) | ALDH1A1HPGDCYP3A4HSD17B10USP2 | |
| SCHEMBL31027412 | 0.83 | ALDH1A1 (0.45) | ALDH1A1HPGDCYP3A4HSD17B10USP2 | |
| SCHEMBL25275190 | 0.83 | ALDH1A1 (0.45) | ALDH1A1HPGDCYP3A4HSD17B10USP2 | |
| SCHEMBL25725472 | 0.81 | HRH4 (0.69) | HRH4ALDH1A1HPGDCYP3A4HSD17B10 | |
| SCHEMBL30456119 | 0.79 | KIT (0.49) | ALDH1A1HPGDCYP3A4HSD17B10USP2 | |
| SCHEMBL30406110 | 0.76 | HSD17B10 (0.44) | ALDH1A1HPGDCYP3A4HSD17B10USP2 | |
| SCHEMBL25725483 | 0.75 | HRH4 (0.34) | HRH4MEN1LMNAKMT2ATSHR | |
| SCHEMBL30455652 | 0.74 | JAK2 (0.41) | ALDH1A1HPGDCYP3A4HSD17B10USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107687-A1 | INHIBITORS OF MENIN-MLL INTERACTION | BALA THERAPEUTICS, INC. (US) | 2023-06-15 | — | — | WO | disclosed |