Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 11/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 9/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.41 |
| ▸ | USP2 | O75604 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 6/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30456119 | 0.82 | KIT (0.49) | HSD17B10ALDH1A1CYP3A4CYP2D6HPGD | |
| SCHEMBL25275190 | 0.81 | ALDH1A1 (0.45) | HSD17B10ALDH1A1CYP3A4CYP2D6HPGD | |
| SCHEMBL31027412 | 0.81 | ALDH1A1 (0.45) | HSD17B10ALDH1A1CYP3A4CYP2D6HPGD | |
| SCHEMBL30405747 | 0.80 | HTT (0.48) | HSD17B10ALDH1A1OPRD1OPRK1HPGD | |
| SCHEMBL30405196 | 0.78 | PDGFRB (0.41) | ALDH1A1CYP3A4CYP2D6OPRD1OPRK1 | |
| SCHEMBL30405798 | 0.78 | OPRD1 (0.43) | HSD17B10ALDH1A1CYP3A4CYP2D6OPRD1 | |
| SCHEMBL30405888 | 0.77 | PDGFRB (0.41) | ALDH1A1CYP3A4CYP2D6OPRD1OPRK1 | |
| SCHEMBL30406045 | 0.77 | MAPK7 (0.44) | — | |
| SCHEMBL30406358 | 0.75 | MAPT (0.35) | HSD17B10ALDH1A1CYP3A4CYP2D6OPRD1 | |
| SCHEMBL30406184 | 0.75 | OPRD1 (0.38) | HSD17B10ALDH1A1CYP3A4CYP2D6OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4444300-A2 | INHIBITORS OF MENIN-MLL INTERACTION | Bala Therapeutics, Inc. (US) | 2024-10-16 | — | — | EP | disclosed |
| WO-2023107696-A2 | INHIBITORS OF MENIN-MLL INTERACTION | BALA THERAPEUTICS, INC. (US) | 2023-06-15 | — | — | WO | disclosed |