Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 7/20 | 0.37 |
| ▸ | OTUD7B | Q6GQQ9 | 6/20 | 0.37 |
| ▸ | JAK2 | O60674 | 6/20 | 0.35 |
| ▸ | JAK1 | P23458 | 6/20 | 0.35 |
| ▸ | TYK2 | P29597 | 6/20 | 0.35 |
| ▸ | PDE9A | O76083 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25627535 | 0.84 | HRH4 (0.45) | ALDH1A1HPGDHSD17B10USP2CYP3A4 | |
| SCHEMBL25630530 | 0.82 | PTK2 (0.50) | JAK3ALDH1A1HPGDHSD17B10CYP3A4 | |
| SCHEMBL25269396 | 0.80 | ALDH1A1 (0.54) | ALDH1A1HPGDHSD17B10USP2CYP3A4 | |
| SCHEMBL30456080 | 0.80 | ALDH1A1 (0.54) | ALDH1A1HPGDHSD17B10USP2CYP3A4 | |
| SCHEMBL25275190 | 0.80 | ALDH1A1 (0.45) | JAK3ALDH1A1HPGDHSD17B10USP2 | |
| SCHEMBL31027412 | 0.80 | ALDH1A1 (0.45) | JAK3ALDH1A1HPGDHSD17B10USP2 | |
| SCHEMBL30456119 | 0.74 | KIT (0.49) | JAK3ALDH1A1HPGDHSD17B10USP2 | |
| SCHEMBL25725210 | 0.72 | CYP1A2 (0.41) | JAK3JAK2JAK1TYK2ALDH1A1 | |
| SCHEMBL25630734 | 0.72 | CYP1A2 (0.42) | ALDH1A1HPGDHSD17B10USP2CYP3A4 | |
| SCHEMBL25630561 | 0.71 | KIT (0.41) | ALDH1A1HPGDHSD17B10USP2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107687-A1 | INHIBITORS OF MENIN-MLL INTERACTION | BALA THERAPEUTICS, INC. (US) | 2023-06-15 | — | — | WO | disclosed |