Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.40 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25627922 | 0.94 | CHRM5 (0.44) | MEN1KMT2ACYP2D6CYP2C19POLB | |
| SCHEMBL25628128 | 0.84 | GID4 (0.43) | CHRNB2CHRNA4SMN1; SMN2GID4KDM4E | |
| SCHEMBL28535227 | 0.79 | MEN1 (0.46) | MEN1KMT2ACYP2D6CYP2C19POLB | |
| SCHEMBL30812563 | 0.78 | KDM4E (0.46) | MEN1KMT2ACYP2D6CYP2C19POLB | |
| SCHEMBL1764675 | 0.78 | KDM4E (0.46) | MEN1KMT2ACYP2D6CYP2C19POLB | |
| SCHEMBL25235310 | 0.78 | CYP2D6 (0.45) | MEN1KMT2ACYP2D6CYP2C19POLB | |
| SCHEMBL10653671 | 0.78 | IKBKB (0.48) | MEN1KMT2ACYP2D6CYP2C19POLB | |
| SCHEMBL30008129 | 0.78 | KDM4E (0.46) | MEN1KMT2ACYP2D6CYP2C19POLB | |
| SCHEMBL13451469 | 0.78 | HTR2C (0.50) | MEN1KMT2ACYP2D6CYP2C19POLB | |
| SCHEMBL17304029 | 0.78 | HTR2C (0.50) | MEN1KMT2ACYP2D6CYP2C19POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192613-A1 | Charged Ion Channel Blockers and Methods for Use | NOCION THERAPEUTICS INC (US) | 2023-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192613-A1 | Charged Ion Channel Blockers and Methods for Use | TRPV1, TRPV2, TRPV5 | MEN1 3082/4885KMT2A 2429/4885CYP2D6 3350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.