Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 16/20 | 0.57 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.55 |
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2552405 | 0.89 | RXRA (0.57) | MRGPRX4MAOBNR4A2MAOA | |
| SCHEMBL2562094 | 0.89 | MAOB (0.52) | MRGPRX4MAOBNR4A2MAOA | |
| SCHEMBL2563377 | 0.85 | MAOB (0.55) | MAOBNR4A2MAOAPARP10 | |
| SCHEMBL15331400 | 0.81 | MAOB (0.54) | MRGPRX4MAOBNR4A2MAOA | |
| SCHEMBL2556050 | 0.81 | MAOB (0.54) | MAOBNR4A2MAOAPARP10 | |
| SCHEMBL23210154 | 0.79 | LIPE (0.53) | MRGPRX4MAOBNR4A2 | |
| SCHEMBL2559615 | 0.78 | MRGPRX4 (0.56) | MRGPRX4MAOBMAOA | |
| SCHEMBL28396075 | 0.76 | MAOB (0.64) | MRGPRX4MAOBNR4A2MAOAPARP10 | |
| SCHEMBL8033064 | 0.76 | MAOB (0.68) | MRGPRX4MAOBNR4A2MAOA | |
| SCHEMBL30449046 | 0.76 | MAOB (0.68) | MRGPRX4MAOBNR4A2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |
| EP-2558577-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2013-02-20 | — | — | EP | disclosed |
| WO-2011127933-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2011-10-20 | — | — | WO | disclosed |