SCHEMBL25629044

SCHEMBL25629044

c1ccc(-c2ccc(N(c3ccc(-c4ccc(-c5ccc6oc7ccccc7c6c5)c(-c5ccccc5)c4)cc3)c3ccccc3-c3ccccc3)c(-c3ccccc3)c2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 4/20 0.38
PLA2G4A P47712 4/20 0.38
PLA2G10 O15496 1/20 0.34
HSP90AA1 P07900 1/20 0.34
HSP90AB1 P08238 1/20 0.34
MEN1 O00255 2/20 0.34
NPC1 O15118 2/20 0.34
MAPT P10636 2/20 0.34
RAB9A P51151 2/20 0.34
KMT2A Q03164 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 1/20 0.34
HPGD P15428 1/20 0.34
ALOX5 P09917 1/20 0.33
LMNA P02545 3/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
AHR P35869 1/20 0.31
APAF1 O14727 1/20 0.31
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25629040 0.96 PLA2G2A (0.40) PLA2G2APLA2G4APLA2G10HSP90AA1HSP90AB1
SCHEMBL24999194 0.95 PLA2G2A (0.40) PLA2G2APLA2G4APLA2G10HSP90AA1HSP90AB1
SCHEMBL25629042 0.95 PLA2G2A (0.40) PLA2G2APLA2G4APLA2G10HSP90AA1HSP90AB1
SCHEMBL25629043 0.94 PLA2G2A (0.40) PLA2G2APLA2G4APLA2G10HSP90AA1HSP90AB1
SCHEMBL18212019 0.92 PLA2G2A (0.44) PLA2G2APLA2G4APLA2G10HSP90AA1HSP90AB1
SCHEMBL25629045 0.91 PLA2G2A (0.36) PLA2G2APLA2G4APLA2G10HSP90AA1HSP90AB1
SCHEMBL22435673 0.91 PLA2G2A (0.37) PLA2G2APLA2G4APLA2G10HSP90AA1HSP90AB1
SCHEMBL22435678 0.91 PLA2G2A (0.37) PLA2G2APLA2G4APLA2G10HSP90AA1HSP90AB1
SCHEMBL22435682 0.90 PLA2G2A (0.38) PLA2G2APLA2G4APLA2G10HSP90AA1HSP90AB1
SCHEMBL18212084 0.89 PLA2G2A (0.44) PLA2G2APLA2G4APLA2G10HSP90AA1HSP90AB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230200222-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-06-22 US disclosed
US-20230200222-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-06-22 US disclosed
US-11678569-B2 Compound, material for organic electroluminescent elements, organic electroluminescent element, and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2023-06-13 US disclosed
US-11678569-B2 Compound, material for organic electroluminescent elements, organic electroluminescent element, and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2023-06-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230200222-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE PIEZO1, LEF1, L1CAM PLA2G2A 4621/4885PLA2G4A 4785/4885PLA2G10 4387/4885
US-11678569-B2 Compound, material for organic electroluminescent elements, organic electroluminescent element, and electronic device PIEZO1, LEF1, L1CAM PLA2G2A 4621/4885PLA2G4A 4785/4885PLA2G10 4387/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.