Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 13/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.42 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.42 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.41 |
| ▸ | VNN1 | O95497 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.40 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13245891 | 0.89 | EPHX2 (0.47) | CHRNB2CHRNA3CHRNA4CHRNB3CHRNA6 | |
| SCHEMBL12800957 | 0.88 | VNN1 (0.40) | PIK3CDVNN1ALDH1A1 | |
| SCHEMBL12800961 | 0.88 | VNN1 (0.40) | PIK3CDVNN1ALDH1A1 | |
| SCHEMBL12801525 | 0.85 | CHRNB2 (0.52) | PIK3CDCHRNB2CHRNA3CHRNA4CHRNB3 | |
| SCHEMBL20878024 | 0.85 | MEN1 (0.39) | PIK3CDVNN1PIK3CAALDH1A1 | |
| SCHEMBL12801551 | 0.84 | ALDH1A1 (0.46) | PIK3CDCHRNB2CHRNA3CHRNA4CHRNB3 | |
| SCHEMBL21929958 | 0.84 | VNN1 (0.41) | VNN1ALDH1A1 | |
| SCHEMBL21930188 | 0.84 | VNN1 (0.41) | VNN1ALDH1A1 | |
| SCHEMBL15932469 | 0.84 | PIK3CD (0.43) | PIK3CDCHRNB2CHRNA3CHRNA4CHRNB3 | |
| SCHEMBL10272743 | 0.84 | PIK3CD (0.43) | PIK3CDCHRNB2CHRNA3CHRNA4CHRNB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023098825-A1 | SOS1 INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | 勤浩医药（苏州）有限公司 | 2023-06-08 | — | — | WO | disclosed |