Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.57 |
| ▸ | PLAAT5 | Q96KN8 | 5/20 | 0.56 |
| ▸ | PLAAT4 | Q9UL19 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4279627 | 0.86 | KEAP1 (0.73) | KEAP1ALDH1A1FFAR1PLAAT5PLAAT4 | |
| SCHEMBL29078123 | 0.82 | KEAP1 (0.67) | KEAP1ALDH1A1FFAR1PLAAT5PLAAT4 | |
| SCHEMBL12174587 | 0.82 | KEAP1 (0.67) | KEAP1ALDH1A1FFAR1PLAAT5PLAAT4 | |
| SCHEMBL258545 | 0.82 | KEAP1 (0.67) | KEAP1ALDH1A1FFAR1PLAAT5PLAAT4 | |
| SCHEMBL10352043 | 0.80 | KEAP1 (0.64) | KEAP1ALDH1A1FFAR1PLAAT5PLAAT4 | |
| SCHEMBL13035854 | 0.78 | KEAP1 (0.61) | KEAP1ALDH1A1FFAR1PLAAT5PLAAT4 | |
| SCHEMBL6629478 | 0.78 | CES2 (0.74) | KEAP1ALDH1A1FFAR1PLAAT5PLAAT4 | |
| SCHEMBL660787 | 0.78 | KEAP1 (0.61) | KEAP1ALDH1A1FFAR1PLAAT5PLAAT4 | |
| SCHEMBL11141595 | 0.78 | KEAP1 (0.61) | KEAP1ALDH1A1FFAR1PLAAT5PLAAT4 | |
| SCHEMBL5566614 | 0.78 | HDAC1 (0.69) | KEAP1ALDH1A1FFAR1PLAAT5PLAAT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230150254-A1 | ON-PRESS DEVELOPMENT TYPE LITHOGRAPHIC PRINTING PLATE PRECURSOR, METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE, AND LITHOGRAPHIC PRINTING METHOD | FUJIFILM CORPORATION (JP) | 2023-05-18 | — | — | US | disclosed |