Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.67 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.60 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.56 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10352043 | 0.98 | KEAP1 (0.64) | KEAP1FFAR1ALDH1A1PLAAT5PLAAT4 | |
| Acetic Acid SCHEMBL27883812 | 0.94 | ALDH1A1 (0.67) | KEAP1FFAR1ALDH1A1PLAAT5PLAAT4 | |
| SCHEMBL4279627 | 0.90 | KEAP1 (0.73) | KEAP1FFAR1ALDH1A1PLAAT5PLAAT4 | |
| SCHEMBL28742807 | 0.87 | FFAR1 (0.71) | KEAP1FFAR1HDAC2HDAC8HDAC6 | |
| SCHEMBL710419 | 0.86 | HDAC1 (0.69) | KEAP1FFAR1ALDH1A1PLAAT5PLAAT4 | |
| SCHEMBL29078123 | 0.86 | KEAP1 (0.67) | KEAP1FFAR1ALDH1A1PLAAT5PLAAT4 | |
| SCHEMBL3270086 | 0.85 | MAPT (0.68) | PLAAT5PLAAT4HDAC2HDAC8HDAC6 | |
| SCHEMBL8511630 | 0.83 | MAPT (0.71) | PLAAT5PLAAT4HDAC2HDAC8HDAC6 | |
| SCHEMBL27851418 | 0.83 | MMP12 (0.58) | KEAP1FFAR1ALDH1A1PLAAT5PLAAT4 | |
| SCHEMBL7270063 | 0.82 | FFAR1 (0.74) | FFAR1PLAAT5PLAAT4CES1PLAAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 616 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120005847-A | Alpha-hydroxy-beta-keto acid synthase for catalyzing alpha-keto acid coupling reaction | 北京大学 | 2025-05-16 | — | — | CN | claimed |
| CN-118580143-A | Preparation method of 4-phenylbutyric acid and derivatives thereof | 北京大学 | 2024-09-03 | — | — | CN | claimed |
| CN-118028837-A | Amino Acid Synthesis Method | 中山大学 | 2024-05-14 | — | — | CN | claimed |
| CN-117265554-A | Method for preparing thioester derivative by electrocatalytic reaction | 江苏中利集团股份有限公司 | 2023-12-22 | — | — | CN | claimed |
| CN-114196642-B | Glutamate dehydrogenase variants and their use in the preparation of L-amino acids | 浙江大学杭州国际科创中心 | 2023-12-05 | — | — | CN | claimed |
| WO-2023198025-A1 | SYNTHESIS METHOD AND SYNTHESIS DEVICE FOR ORGANIC NITROGEN-CONTAINING COMPOUND | 中山大学 | 2023-10-19 | — | — | WO | claimed |
| CN-115851641-A | Fusion enzyme for efficiently producing (R) -2-hydroxy-4-phenylbutyric ethyl butyrate and application thereof | 浙江工业大学 | 2023-03-28 | — | — | CN | claimed |
| CN-115820622-A | Double-enzyme self-assembly compound and application of compound in synthesizing (R) -2-hydroxy-4-phenylbutyrate | 浙江工业大学 | 2023-03-21 | — | — | CN | claimed |
| CN-114196642-A | Glutamate dehydrogenase variants and their use in the preparation of L-amino acids | 浙江大学杭州国际科创中心 | 2022-03-18 | — | — | CN | claimed |
| CN-113817697-A | Phenylalanine dehydrogenase mutant and application thereof in synthesis of L-homophenylalanine | 江南大学 | 2021-12-21 | — | — | CN | claimed |
| EP-0387058-A1 | Process for preparing benzylpyruvic acids and esters | MERCK & CO. INC. (US) | 1990-09-12 | — | — | EP | claimed |
| US-4956490-A | Process for preparing benzylpyruvic acids and esters | MERCK & CO., INC. (US) | 1990-09-11 | — | — | US | claimed |
| EP-0135846-B1 | PRODUCTION OF L-AMINO ACIDS BY TRANSAMINATION | GENETICS INSTITUTE, INC. (US) | 1990-08-16 | — | — | EP | claimed |
| US-4837354-A | Process for making and isolating (R)-2-hydroxy-4-phenylbutyric acid and esters | MERRELL DOW PHARMACEUTICALS INC. (US) | 1989-06-06 | — | — | US | claimed |
| EP-0280285-A2 | Process for making and isolating (R)-2-hydroxy 4-phenylbutyric acid and esters | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-08-31 | — | — | EP | claimed |
| US-4525454-A | REACTING 2-KETOACID AND L-ASPARTIC ACID IN PRESENCE OF TRANSAMINASE ENZYME | GENETICS INSTITUTE, INC. (US) | 1985-06-25 | — | — | US | claimed |
| EP-0135846-A2 | Production of L-amino acids by transamination | GENETICS INSTITUTE, INC. (US) | 1985-04-03 | — | — | EP | claimed |
| US-4481368-A | Process for preparing α-keto-carboxylic acids from acyl halides | ETHYL CORPORATION (US) | 1984-11-06 | — | — | US | claimed |
| US-4481369-A | VIA TRICARBONYL(TRIPHENYLPOSPHINE) COBALTATE | ETHYL CORPORATION (US) | 1984-11-06 | — | — | US | claimed |
| EP-0012117-B1 | PROCESS FOR THE PREPARATION OF 2,3,5-TRICHLOROPYRIDINE; 2,4,4-TRICHLORO-4-FORMYL-BUTYRONITRILE AND PROCESS FOR ITS PREPARATION | CIBA-GEIGY AG (CH) | 1982-02-10 | — | — | EP | claimed |