SCHEMBL25634864

SCHEMBL25634864

c1ccc2c(c1)Cc1ccccc1-c1cccn1-c1ccccc1-2

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR3E A5X5Y0 4/20 0.40
HTR3B O95264 4/20 0.40
HTR3A P46098 4/20 0.40
HTR3D Q70Z44 4/20 0.40
HTR3C Q8WXA8 4/20 0.40
MAOA P21397 1/20 0.39
KDM4E B2RXH2 2/20 0.38
NPC1 O15118 2/20 0.38
MAPT P10636 2/20 0.38
RAB9A P51151 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
ALDH1A1 P00352 1/20 0.38
LMNA P02545 1/20 0.38
HPGD P15428 1/20 0.38
KMT2A Q03164 3/20 0.37
CASP3 P42574 2/20 0.37
CASP6 P55212 2/20 0.37
SENP8 Q96LD8 2/20 0.37
SENP7 Q9BQF6 2/20 0.37
SENP6 Q9GZR1 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25634863 0.88 MAOA (0.38) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL25634873 0.83 KMT2A (0.36) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL25634878 0.81 MAOA (0.36) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL25634862 0.81 HTR3E (0.46) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL25634879 0.79 TSHR (0.40) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL25634865 0.79 DNMT1 (0.39) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL25634874 0.78 HTR3E (0.38) HTR3EHTR3BHTR3AHTR3DHTR3C
Fluorene SCHEMBL545861 0.71 MAOA (0.68) MAOAKDM4ENPC1MAPTRAB9A
Fluorene SCHEMBL29355380 0.71 MAOA (0.68) MAOAKDM4ENPC1MAPTRAB9A
Fluorene SCHEMBL31388525 0.71 MAOA (0.68) MAOAKDM4ENPC1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230192714-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230192714-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ODC1 HTR3E 1963/4885HTR3B 1973/4885HTR3A 2124/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.