SCHEMBL25635129

SCHEMBL25635129

Cc1ccc2c3cccc4c5ccccc5c5cccc6c7ccccc7n(c7ccccc7n(c2c1)c43)c56

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALKBH5 Q6P6C2 1/20 0.43
FTO Q9C0B1 1/20 0.43
MAPT P10636 4/20 0.40
HTT P42858 2/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
POLB P06746 2/20 0.40
KDM4E B2RXH2 1/20 0.40
ALDH1A1 P00352 1/20 0.40
HPGD P15428 1/20 0.40
CYP1A2 P05177 1/20 0.39
KIF11 P52732 1/20 0.37
LMNA P02545 2/20 0.37
GPR3 P46089 1/20 0.36
CYP2A6 P11509 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
ELANE P08246 1/20 0.34
PTPN1 P18031 1/20 0.34
PGR P06401 1/20 0.33
RORA P35398 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25640742 0.98 ALKBH5 (0.44) ALKBH5FTOMAPTHTTMEN1
SCHEMBL16621615 0.96 ALKBH5 (0.46) ALKBH5FTOMAPTHTTMEN1
SCHEMBL25635139 0.95 ALKBH5 (0.42) ALKBH5FTOMAPTHTTMEN1
SCHEMBL25635001 0.88 ALKBH5 (0.44) ALKBH5FTOMAPTHTTMEN1
SCHEMBL24390114 0.88 ALKBH5 (0.41) ALKBH5FTOMAPTHTTMEN1
SCHEMBL25880172 0.87 ALKBH5 (0.43) ALKBH5FTOMAPTHTTMEN1
SCHEMBL25635477 0.86 ALKBH5 (0.46) ALKBH5FTOMAPTHTTMEN1
SCHEMBL10153568 0.86 ALKBH5 (0.46) ALKBH5FTOMAPTHTTMEN1
SCHEMBL25880217 0.85 ALKBH5 (0.40) ALKBH5FTOMAPTHTTMEN1
SCHEMBL26179694 0.85 PGR (0.41) MAPTHTTMEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230192714-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230192714-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ODC1 ALKBH5 604/4885FTO 39/4885MAPT 1568/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.