SCHEMBL25880217

SCHEMBL25880217

Cc1ccc2c3cc(C)cc4c3n(c2c1)c1cccc2c3ccccc3n4c21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALKBH5 Q6P6C2 1/20 0.40
FTO Q9C0B1 1/20 0.40
CYP1A2 P05177 3/20 0.36
MAPT P10636 4/20 0.34
HTT P42858 3/20 0.34
LMNA P02545 2/20 0.34
KIF11 P52732 1/20 0.34
KDM4E B2RXH2 2/20 0.34
MEN1 O00255 1/20 0.34
ALDH1A1 P00352 1/20 0.34
POLB P06746 1/20 0.34
HPGD P15428 1/20 0.34
KMT2A Q03164 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
CYP2A6 P11509 3/20 0.33
GPR3 P46089 1/20 0.33
TDP1 Q9NUW8 2/20 0.32
PTPN1 P18031 1/20 0.32
BCHE P06276 1/20 0.32
ACHE P22303 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25880215 0.94 ALKBH5 (0.40) ALKBH5FTOCYP1A2MAPTHTT
SCHEMBL25880160 0.94 ALKBH5 (0.44) ALKBH5FTOCYP1A2MAPTHTT
SCHEMBL25635139 0.90 ALKBH5 (0.42) ALKBH5FTOCYP1A2MAPTHTT
SCHEMBL25880172 0.90 ALKBH5 (0.43) ALKBH5FTOCYP1A2MAPTHTT
SCHEMBL16621615 0.89 ALKBH5 (0.46) ALKBH5FTOCYP1A2MAPTHTT
SCHEMBL25880167 0.88 GPR3 (0.41) ALKBH5FTOCYP1A2MAPTHTT
SCHEMBL24390065 0.87 ALKBH5 (0.44) ALKBH5FTOCYP1A2MAPTHTT
SCHEMBL25640742 0.87 ALKBH5 (0.44) ALKBH5FTOCYP1A2MAPTHTT
SCHEMBL25880198 0.87 CYP1A2 (0.37) CYP1A2MAPTHTTLMNAKIF11
SCHEMBL25635129 0.85 ALKBH5 (0.43) ALKBH5FTOCYP1A2MAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230240135-A1 HETEROCYLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE HETEROCYCLIC COMPOUND AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230240135-A1 HETEROCYLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE HETEROCYCLIC COMPOUND AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE CRY1, LAGE3, NQO1 ALKBH5 1815/4885FTO 494/4885CYP1A2 21/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.