SCHEMBL25636280

SCHEMBL25636280

c1ccc(-c2cc(Nc3cccc4c3sc3ccccc34)c3oc4ccccc4c3c2)cc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP14 Q460N5 1/20 0.34
PLA2G2A P14555 2/20 0.34
PLA2G4A P47712 2/20 0.34
ESR2 Q92731 2/20 0.34
ALOX5 P09917 2/20 0.34
ALDH1A1 P00352 2/20 0.34
LMNA P02545 2/20 0.34
TNKS O95271 2/20 0.34
TNKS2 Q9H2K2 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
ESR1 P03372 1/20 0.33
PLA2G10 O15496 1/20 0.33
AHR P35869 1/20 0.33
PTGES2 Q9H7Z7 1/20 0.32
LIMK1 P53667 1/20 0.32
PRKDC P78527 2/20 0.31
HPGD P15428 2/20 0.31
KDM4E B2RXH2 1/20 0.31
TSHR P16473 1/20 0.31
CASP3 P42574 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20312827 0.85 PARP14 (0.40) PARP14ESR2ALOX5ALDH1A1LMNA
SCHEMBL31196102 0.85 PARP14 (0.40) PARP14ESR2ALOX5ALDH1A1LMNA
SCHEMBL23314012 0.81 ALOX5 (0.40) PARP14ESR2ALOX5ALDH1A1LMNA
SCHEMBL23372792 0.80 TNKS (0.37) PLA2G2APLA2G4AALDH1A1TNKSTNKS2
SCHEMBL24472407 0.79 CDC14B (0.40) PARP14ESR2ALOX5ALDH1A1LMNA
SCHEMBL24834378 0.77 ALOX5 (0.46) PARP14ESR2ALOX5AHRPTGES2
SCHEMBL25666999 0.77 ALOX5 (0.38) PARP14PLA2G2APLA2G4AALOX5PLA2G10
SCHEMBL23419058 0.77 MMP2 (0.46) PLA2G2APLA2G4AALDH1A1LMNATNKS
SCHEMBL17057176 0.77 ALOX5 (0.44) PARP14PLA2G2APLA2G4AESR2ALOX5
SCHEMBL24171467 0.77 ALOX5 (0.44) PARP14PLA2G2APLA2G4AESR2ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230189639-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2023-06-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230189639-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF ETV6, OR51E2, NFE2L2 PARP14 3324/4885PLA2G2A 4331/4885PLA2G4A 3902/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.