SCHEMBL2563679

SCHEMBL2563679

[CH2]c1ccc(CC)cc1OC

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.52
CA2 P00918 1/20 0.47
ALDH1A1 P00352 3/20 0.44
PPARG P37231 1/20 0.44
PPARD Q03181 1/20 0.44
PPARA Q07869 1/20 0.44
TUBB1 Q9H4B7 2/20 0.43
ATM Q13315 2/20 0.41
KDM4E B2RXH2 1/20 0.41
CYP3A4 P08684 3/20 0.41
ALOX5 P09917 1/20 0.41
AR P10275 1/20 0.41
PTGS1 P23219 1/20 0.41
TRPM8 Q7Z2W7 1/20 0.41
LMNA P02545 1/20 0.40
HTT P42858 1/20 0.40
KMT2A Q03164 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
MMP1 P03956 1/20 0.40
POLB P06746 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2559403 0.84 ATM (0.47) CA2ALDH1A1PPARGPPARAATM
SCHEMBL11674168 0.83 CA2 (0.47) PTGS2CA2ALDH1A1PPARGPPARD
SCHEMBL27708582 0.82 CA2 (0.45) CA2ALDH1A1PPARGPPARDPPARA
SCHEMBL31428 0.80 CA2 (0.71) PTGS2CA2ALDH1A1PPARGPPARD
SCHEMBL31275634 0.80 CA2 (0.71) PTGS2CA2ALDH1A1PPARGPPARD
SCHEMBL2568263 0.79 ALDH1A1 (0.73) ALDH1A1PPARGPPARDPPARAKDM4E
Water SCHEMBL8587595 0.78 CA2 (0.68) PTGS2CA2ALDH1A1PPARGPPARD
Ammonia Solution, Strong SCHEMBL266403 0.78 CA2 (0.68) PTGS2CA2ALDH1A1PPARGPPARD
SCHEMBL2563683 0.77 PTGS2 (0.54) PTGS2CA2ALDH1A1PPARGPPARD
SCHEMBL12797853 0.77 PTGS2 (0.54) PTGS2CA2ALDH1A1TUBB1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2561051-A1 ORGANIC CARBONATES WITH VANILLA ODOR Firmenich SA (CH) 2013-02-27 EP disclosed
WO-2011132098-A1 ORGANIC CARBONATES WITH VANILLA ODOR FIRMENICH SA (CH) 2011-10-27 WO disclosed