Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 8/20 | 0.36 |
| ▸ | MGLL | Q99685 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | MDH1 | P40925 | 1/20 | 0.32 |
| ▸ | MDH2 | P40926 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20567150 | 0.88 | MGLL (0.46) | MGLLFAAH | |
| SCHEMBL30302082 | 0.88 | MGLL (0.46) | MGLLFAAH | |
| SCHEMBL20567175 | 0.83 | GPR119 (0.46) | FAAHNOTUMGPR119IDO1TDO2 | |
| SCHEMBL20571263 | 0.78 | NOTUM (0.43) | MGLLFAAHNOTUML3MBTL1 | |
| SCHEMBL25487268 | 0.78 | FAAH (0.42) | MGLLFAAH | |
| SCHEMBL20567003 | 0.76 | FAAH (0.55) | MGLLFAAH | |
| SCHEMBL30302147 | 0.76 | FAAH (0.55) | MGLLFAAH | |
| SCHEMBL23015481 | 0.75 | NOTUM (0.35) | NOTUM | |
| SCHEMBL20571739 | 0.74 | ATM (0.39) | MGLLNOTUML3MBTL1 | |
| SCHEMBL25487263 | 0.72 | GPR119 (0.46) | GPR119IDO1TDO2IDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4198024-A1 | PYRAZOLE MAGL INHIBITORS | H. Lundbeck A/S (DK) | 2023-06-21 | — | — | EP | disclosed |