Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.55 |
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HK1 | P19367 | 1/20 | 0.40 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23120078 | 1.00 | MAOA (0.55) | MAOAMAOBADRA2AADRA2BADRA2C | |
| SCHEMBL7913558 | 0.85 | ADRA2A (0.59) | ADRA2AADRA2BADRA2CPLAUALDH1A1 | |
| SCHEMBL7913597 | 0.81 | MAOA (0.55) | MAOAMAOBADRA2AADRA2BADRA2C | |
| SCHEMBL13915657 | 0.77 | MAOA (0.55) | MAOAMAOBADRA2AADRA2BADRA2C | |
| SCHEMBL28860012 | 0.77 | MAOA (0.55) | MAOAMAOBADRA2AADRA2BADRA2C | |
| SCHEMBL3283243 | 0.74 | ALDH1A1 (0.67) | ALDH1A1TRPA1KMT2AMEN1ATM | |
| SCHEMBL3283246 | 0.74 | ALDH1A1 (0.67) | ALDH1A1TRPA1KMT2AMEN1ATM | |
| SCHEMBL20865423 | 0.73 | MAOA (0.71) | MAOAMAOBADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL29087184 | 0.72 | ALDH1A1 (0.63) | ALDH1A1TRPA1KMT2AMEN1ATM | |
| SCHEMBL2560994 | 0.72 | MAOA (0.58) | MAOAMAOBALDH1A1TRPA1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110746465-B | Osmium complex, preparation method and application thereof | 深圳大学 | 2021-03-30 | — | — | CN | claimed |
| WO-2021051709-A1 | OSMIUM COMPLEX, PREPARATION METHOD THEREFOR AND USE THEREOF | 深圳大学 | 2021-03-25 | — | — | WO | claimed |
| CN-110746465-A | Osmium complex, preparation method and application thereof | 深圳大学 | 2020-02-04 | — | — | CN | claimed |
| CN-110746465-B | Osmium complex, preparation method and application thereof | 深圳大学 | 2021-03-30 | — | — | CN | disclosed |
| CN-110746465-B | Osmium complex, preparation method and application thereof | 深圳大学 | 2021-03-30 | — | — | CN | disclosed |
| WO-2021051709-A1 | OSMIUM COMPLEX, PREPARATION METHOD THEREFOR AND USE THEREOF | 深圳大学 | 2021-03-25 | — | — | WO | disclosed |
| CN-110746465-A | Osmium complex, preparation method and application thereof | 深圳大学 | 2020-02-04 | — | — | CN | disclosed |
| CN-110746465-A | Osmium complex, preparation method and application thereof | 深圳大学 | 2020-02-04 | — | — | CN | disclosed |
| CN-108690619-A | The preparation method of rare earth metal adulterated with Ca and Ti ore quantum dot | TCL集团股份有限公司 | 2018-10-23 | — | — | CN | disclosed |
| EP-3205657-A1 | OSMIUM (II) ARENE IMINO ANTI-CANCER COMPLEXES | University of Warwick (GB) | 2017-08-16 | — | — | EP | disclosed |
| US-9598448-B2 | Osmium (II) arene imino anti-cancer complexes | UNIVERSITY OF WARWICK (GB) | 2017-03-21 | — | — | US | disclosed |
| EP-2560980-B1 | OSMIUM (II) ARENE AZO ANTI-CANCER COMPLEXES | UNIV WARWICK (GB) | 2017-01-25 | — | — | EP | disclosed |
| CN-103575728-B | Based on filter paper, colorimetric sensor array is used for trace heavy metal ion detection method | 中国科学院大连化学物理研究所 | 2016-12-21 | — | — | CN | disclosed |
| US-20160272663-A1 | OSMIUM (II) ARENE AZO ANTI-CANCER COMPLEXES | UNIVERSITY OF WARWICK (GB) | 2016-09-22 | — | — | US | disclosed |
| CN-103108880-B | Osmium (II) aromatic hydrocarbons azo and imino group anticancer complexes | 华威大学 | 2016-08-03 | — | — | CN | disclosed |
| US-9296772-B2 | Osmium (II) arene azo anti-cancer complexes | THE UNIVERSITY OF WARWICK (GB) | 2016-03-29 | — | — | US | disclosed |
| EP-2560980-A2 | OSMIUM (II) ARENE AZO ANTI-CANCER COMPLEXES | University of Warwick (GB) | 2013-02-27 | — | — | EP | disclosed |
| US-20130040925-A1 | OSMIUM (II) ARENE AZO ANTI-CANCER COMPLEXES | UNIVERSITY OF WARWICK (GB) | 2013-02-14 | — | — | US | disclosed |
| WO-2011131925-A2 | OSMIUM (II) ARENE AZO ANTI-CANCER COMPLEXES | UNIVERSITY OF WARWICK (GB) | 2011-10-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160272663-A1 | OSMIUM (II) ARENE AZO ANTI-CANCER COMPLEXES | TP53, SLC30A5, IDH1 | MAOA 4342/4885MAOB 3959/4885ADRA2A 2679/4885 |
| US-20130040925-A1 | OSMIUM (II) ARENE AZO ANTI-CANCER COMPLEXES | TP53, SLC30A5, IDH1 | MAOA 4342/4885MAOB 3959/4885ADRA2A 2679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.