Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25640278 | 0.85 | OPRM1 (0.33) | KCNH2 | |
| SCHEMBL9924111 | 0.76 | NOS3 (0.31) | — | |
| SCHEMBL15739795 | 0.74 | KDM1A (0.44) | — | |
| SCHEMBL12665794 | 0.74 | — | — | |
| SCHEMBL21648795 | 0.72 | — | — | |
| SCHEMBL22624226 | 0.71 | — | — | |
| SCHEMBL26455588 | 0.71 | CYP2D6 (0.37) | — | |
| SCHEMBL25133319 | 0.70 | SIGMAR1 (0.33) | KCNH2 | |
| SCHEMBL20314528 | 0.70 | — | — | |
| SCHEMBL25640277 | 0.69 | CYP2D6 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104043-A1 | ANTI-APOPTOTIC PROTEIN BCL-2 INHIBITOR, PHARMACEUTICAL COMPOSITION AND USES THEREOF | 杭州和正医药有限公司 | 2023-06-15 | — | — | WO | disclosed |