Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 2/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | LIG1 | P18858 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4915367 | 0.86 | CTSD (0.68) | CTSDMEN1KMT2ACA1CA2 | |
| SCHEMBL6329484 | 0.86 | CTSD (0.72) | CTSDMEN1KMT2ACA1CA2 | |
| SCHEMBL295407 | 0.82 | CTSD (1.00) | CTSDMEN1KMT2AALDH1A1GAA | |
| SCHEMBL7748621 | 0.82 | CTSD (0.68) | CTSDMEN1KMT2ACA1CA2 | |
| SCHEMBL16193193 | 0.82 | CTSD (0.68) | CTSDMEN1KMT2ACA1CA2 | |
| SCHEMBL30349208 | 0.82 | CTSD (1.00) | CTSDMEN1KMT2AALDH1A1GAA | |
| SCHEMBL11326953 | 0.81 | CTSD (0.66) | CTSDMEN1KMT2ACA1CA2 | |
| SCHEMBL17479848 | 0.81 | CTSD (0.66) | CTSDMEN1KMT2ACA1CA2 | |
| SCHEMBL239328 | 0.80 | CTSD (0.63) | CTSDMEN1KMT2ACA1CA2 | |
| SCHEMBL30547074 | 0.80 | CTSD (0.63) | CTSDMEN1KMT2ACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115666653-A | Antibody-drug conjugates | 斯皮雷亚有限公司 | 2023-01-31 | — | — | CN | disclosed |
| CN-113226378-A | Antibody-drug conjugates | 斯皮雷亚有限公司 | 2021-08-06 | — | — | CN | disclosed |
| EP-2560634-A1 | NITRIC OXIDE RELEASING PRODRUGS OF THERAPEUTIC AGENTS | Piramal Enterprises Limited (IN) | 2013-02-27 | — | — | EP | disclosed |
| WO-2011132171-A1 | NITRIC OXIDE RELEASING PRODRUGS OF THERAPEUTIC AGENTS | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2011-10-27 | — | — | WO | disclosed |