Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7748621 | 0.87 | CTSD (0.68) | CTSDKMT2AMEN1CA1CA2 | |
| SCHEMBL17479848 | 0.85 | CTSD (0.66) | CTSDKMT2AMEN1CA1CA2 | |
| SCHEMBL7195412 | 0.84 | ALDH1A1 (0.48) | CTSDKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL12468767 | 0.84 | CTSD (0.69) | CTSDKMT2AMEN1CA1CA2 | |
| SCHEMBL6329484 | 0.82 | CTSD (0.72) | CTSDKMT2AMEN1CA1CA2 | |
| SCHEMBL3234187 | 0.82 | CTSD (0.62) | CTSDKMT2AMEN1CA1CA2 | |
| SCHEMBL2564034 | 0.81 | CTSD (0.70) | CTSDKMT2AMEN1CA1CA2 | |
| SCHEMBL9825473 | 0.81 | SLC6A3 (0.66) | CTSDKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL28767126 | 0.81 | CTSD (0.65) | CTSDKMT2AMEN1CA1CA2 | |
| SCHEMBL27548437 | 0.80 | CTSD (0.58) | CTSDKMT2AMEN1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4306930-A | INCORPORATING A HYDRAZIDE OR DIHYDRAZIDE AND THEN VULCANIZING IN CONTACT WITH A METAL | CIBA-GEIGY CORPORATION (US) | 1981-12-22 | — | — | US | disclosed |
| US-4077948-A | N-SALICYLIDENE-N*-SALICYLHYDRAZIDES | CIBA-GEIGY CORPORATION (US) | 1978-03-07 | — | — | US | disclosed |