Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 5/20 | 0.36 |
| ▸ | HTR2A | P28223 | 4/20 | 0.36 |
| ▸ | DRD3 | P35462 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.36 |
| ▸ | EED | O75530 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25640415 | 0.93 | LMNA (0.41) | LMNAL3MBTL1POLBDRD2 | |
| SCHEMBL25195989 | 0.93 | LMNA (0.41) | LMNAL3MBTL1POLBDRD2 | |
| SCHEMBL30287308 | 0.93 | LMNA (0.41) | LMNAL3MBTL1POLBDRD2 | |
| SCHEMBL25265194 | 0.87 | LMNA (0.36) | LMNAL3MBTL1POLB | |
| SCHEMBL30287134 | 0.87 | LMNA (0.36) | LMNAL3MBTL1POLB | |
| SCHEMBL23924984 | 0.87 | LMNA (0.36) | LMNAL3MBTL1POLB | |
| SCHEMBL25478885 | 0.83 | TACR1 (0.38) | LMNARECQLALDH1A1KMT2A | |
| SCHEMBL25640410 | 0.83 | TACR1 (0.38) | LMNARECQLALDH1A1KMT2A | |
| SCHEMBL25640538 | 0.82 | LMNA (0.51) | LMNAALDH1A1NPSR1MCHR1 | |
| SCHEMBL25743441 | 0.82 | LMNA (0.51) | LMNAALDH1A1NPSR1MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104043-A1 | ANTI-APOPTOTIC PROTEIN BCL-2 INHIBITOR, PHARMACEUTICAL COMPOSITION AND USES THEREOF | 杭州和正医药有限公司 | 2023-06-15 | — | — | WO | disclosed |