Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30287308 | 1.00 | LMNA (0.41) | LMNADRD2CHRM4L3MBTL1MTNR1A | |
| SCHEMBL25195989 | 1.00 | LMNA (0.41) | LMNADRD2CHRM4L3MBTL1MTNR1A | |
| SCHEMBL25640540 | 0.93 | LMNA (0.48) | LMNADRD2L3MBTL1POLB | |
| SCHEMBL23924984 | 0.86 | LMNA (0.36) | LMNAL3MBTL1POLB | |
| SCHEMBL30287134 | 0.86 | LMNA (0.36) | LMNAL3MBTL1POLB | |
| SCHEMBL25265194 | 0.86 | LMNA (0.36) | LMNAL3MBTL1POLB | |
| SCHEMBL25640466 | 0.83 | TACR1 (0.37) | LMNA | |
| SCHEMBL25640465 | 0.81 | CYP2D6 (0.48) | LMNA | |
| SCHEMBL25640506 | 0.80 | TACR1 (0.39) | CHRM4POLB | |
| SCHEMBL25640473 | 0.80 | TACR1 (0.45) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104043-A1 | ANTI-APOPTOTIC PROTEIN BCL-2 INHIBITOR, PHARMACEUTICAL COMPOSITION AND USES THEREOF | 杭州和正医药有限公司 | 2023-06-15 | — | — | WO | disclosed |