SCHEMBL25640599

SCHEMBL25640599

O=C(O)c1ccn(C(=O)N2CC3CC(Oc4cccc(-c5cncnc5)c4)C[C@@H]3C2)n1

nearest known ligand 0.84

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FAAH O00519 8/20 0.84
MGLL Q99685 15/20 0.81

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24971346 1.00 FAAH (0.84) FAAHMGLL
SCHEMBL20571389 1.00 FAAH (0.84) FAAHMGLL
SCHEMBL30302075 1.00 FAAH (0.84) FAAHMGLL
SCHEMBL20920396 1.00 FAAH (0.84) FAAHMGLL
SCHEMBL25830161 0.92 FAAH (0.70) FAAHMGLL
SCHEMBL20920452 0.92 MGLL (0.83) FAAHMGLL
SCHEMBL24970388 0.92 MGLL (0.83) FAAHMGLL
SCHEMBL20920416 0.91 FAAH (1.00) FAAHMGLL
SCHEMBL24970384 0.91 FAAH (1.00) FAAHMGLL
SCHEMBL20920431 0.91 FAAH (1.00) FAAHMGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4198024-A1 PYRAZOLE MAGL INHIBITORS H. Lundbeck A/S (DK) 2023-06-21 EP disclosed