Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.49 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2998236 | 0.85 | APLNR (0.59) | APLNRALDH1A1TSHRTAS1R3TAS1R1 | |
| SCHEMBL15387247 | 0.84 | APLNR (0.49) | APLNRALDH1A1POLBTDP1MAPT | |
| SCHEMBL23888458 | 0.82 | APLNR (0.50) | APLNRALDH1A1POLBTDP1MAPT | |
| SCHEMBL13402596 | 0.81 | APLNR (0.58) | APLNRALDH1A1TSHRTAS1R3TAS1R1 | |
| SCHEMBL491054 | 0.79 | ALDH1A1 (0.51) | APLNRALDH1A1POLBTDP1MAPT | |
| SCHEMBL523291 | 0.78 | APLNR (0.63) | APLNRALDH1A1POLBTDP1MAPT | |
| SCHEMBL884338 | 0.78 | ALDH1A1 (0.58) | APLNRALDH1A1POLBTDP1MAPT | |
| SCHEMBL7443431 | 0.78 | APLNR (0.55) | APLNRALDH1A1POLBTDP1MAPT | |
| SCHEMBL28662641 | 0.78 | APLNR (0.55) | APLNRTAS1R3TAS1R1MEN1KMT2A | |
| SCHEMBL31649081 | 0.78 | APLNR (0.55) | APLNRALDH1A1TSHRTAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2382218-A1 | DELTA-5-DESATURASE INHIBITORS | Takeda Pharmaceutical Company Limited (JP) | 2011-11-02 | — | — | EP | disclosed |
| US-5633243-A | Anti-tumor platinum complexes, their preparation and their therapeutic use | SANKYO COMPANY, LIMITED (JP) | 1997-05-27 | — | — | US | disclosed |
| US-5527905-A | RELATIVELY FEW SIDE EFFECTS, GOOD SOLUBILITY IN WATER | SANKYO COMPANY, LIMITED (JP) | 1996-06-18 | — | — | US | disclosed |
| EP-0290280-A2 | Anti-tumor platinum complexes, their preparation and their therapeutic use | Sankyo Company Limited (JP) | 1988-11-09 | — | — | EP | disclosed |
| US-4587049-A | Azetidinone acetic acid derivatives and process for the preparation thereof | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1986-05-06 | — | — | US | disclosed |
| US-4435322-A | Heterocyclic compounds containing an alkoxycarbonyl and a substituted methyl group | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1984-03-06 | — | — | US | disclosed |
| US-4432901-A | CHEMICAL INTERMEDIATE FOR PENICIULINS, THIENAMYCINS | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1984-02-21 | — | — | US | disclosed |