Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.59 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.55 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29589384 | 0.87 | CD274 (0.61) | APLNRTAS1R3TAS1R1MEN1KMT2A | |
| SCHEMBL29589093 | 0.87 | CD274 (0.61) | APLNRTAS1R3TAS1R1MEN1KMT2A | |
| SCHEMBL28662643 | 0.85 | APLNR (0.55) | APLNRTAS1R3TAS1R1MEN1KMT2A | |
| SCHEMBL28662641 | 0.85 | APLNR (0.55) | APLNRTAS1R3TAS1R1MEN1KMT2A | |
| SCHEMBL2564115 | 0.85 | APLNR (0.55) | APLNRTAS1R3TAS1R1MEN1KMT2A | |
| SCHEMBL29233269 | 0.83 | TAS1R3 (0.54) | APLNRTAS1R3TAS1R1MEN1KMT2A | |
| SCHEMBL13402596 | 0.81 | APLNR (0.58) | APLNRTAS1R3TAS1R1MEN1KMT2A | |
| SCHEMBL24399602 | 0.80 | APLNR (0.65) | APLNRTAS1R3TAS1R1MEN1KMT2A | |
| SCHEMBL2261220 | 0.80 | APLNR (0.65) | APLNRTAS1R3TAS1R1MEN1KMT2A | |
| SCHEMBL2490342 | 0.80 | APLNR (0.56) | APLNRTAS1R3TAS1R1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010087467-A1 | DELTA-5-DESATURASE INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-08-05 | — | — | WO | disclosed |
| US-20100190747-A1 | Fused ring compound and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-07-29 | — | — | US | disclosed |
| EP-0290280-B1 | Anti-tumor platinum complexes, their preparation and their therapeutic use | SANKYO CO (JP) | 1994-01-19 | — | — | EP | disclosed |
| US-4541955-A | Azetidinone-4-carboxylate containing a protected 3-acetyl group and process for their preparation | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1985-09-17 | — | — | US | disclosed |
| US-4434099-A | Beta-lactam compounds containing a protected C-acetyl group, process for their preparation and pharmaceutical compositions containing them | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1984-02-28 | — | — | US | disclosed |
| US-4432901-A | CHEMICAL INTERMEDIATE FOR PENICIULINS, THIENAMYCINS | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1984-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190747-A1 | Fused ring compound and use thereof | CYP46A1, LTB4R2, PTGES | APLNR 1310/4885TAS1R3 3417/4885TAS1R1 3608/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.