Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.62 |
| ▸ | NPC1 | O15118 | 8/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | TP53 | P04637 | 2/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | CASP3 | P42574 | 2/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.56 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.56 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.56 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12218013 | 0.86 | RAB9A (0.70) | RAB9ANPC1SMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL2564673 | 0.83 | RAB9A (0.60) | RAB9ANPC1SMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL2564961 | 0.83 | NPC1 (0.71) | RAB9ANPC1SMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL2566258 | 0.82 | NPC1 (0.66) | RAB9ANPC1SMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL2566373 | 0.81 | SMN1; SMN2 (0.67) | RAB9ANPC1SMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL18774000 | 0.80 | SMN1; SMN2 (0.58) | RAB9ANPC1SMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL30739642 | 0.80 | KMT2A (0.86) | RAB9ANPC1SMN1; SMN2TP53MEN1 | |
| SCHEMBL8361568 | 0.79 | KCNK3 (0.73) | RAB9ANPC1SMN1; SMN2TP53MEN1 | |
| SCHEMBL31556825 | 0.79 | KCNK3 (0.73) | RAB9ANPC1SMN1; SMN2TP53MEN1 | |
| SCHEMBL825718 | 0.77 | NPC1 (0.63) | RAB9ANPC1SMN1; SMN2ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2382194-A2 | COMPOUNDS FOR THE PREVENTION AND TREATMENT OF CARDIOVASCULAR DISEASE | RESVERLOGIX CORP. (CA) | 2011-11-02 | — | — | EP | disclosed |