SCHEMBL25645331

SCHEMBL25645331

CCCCCCC(CC)C1CCN(C)C1

nearest known ligand 0.43

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GNAO1 P09471 6/20 0.43
GNAI3 P08754 5/20 0.43
GNAI1 P63096 5/20 0.43
GUSB P08236 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26137799 0.93 GNAI3 (0.47) GNAO1GNAI3GNAI1GUSB
SCHEMBL22871198 0.92 GNAO1 (0.46) GNAO1GNAI3GNAI1GUSB
SCHEMBL21859738 0.92 GNAO1 (0.46) GNAO1GNAI3GNAI1GUSB
SCHEMBL18885333 0.92 GNAO1 (0.46) GNAO1GNAI3GNAI1GUSB
SCHEMBL23717815 0.92 GNAO1 (0.46) GNAO1GNAI3GNAI1GUSB
SCHEMBL24489194 0.92 GNAO1 (0.46) GNAO1GNAI3GNAI1GUSB
SCHEMBL21725550 0.92 GNAO1 (0.46) GNAO1GNAI3GNAI1GUSB
SCHEMBL24918383 0.92 GNAO1 (0.46) GNAO1GNAI3GNAI1GUSB
SCHEMBL21725544 0.92 GNAO1 (0.46) GNAO1GNAI3GNAI1GUSB
SCHEMBL21025156 0.92 GNAO1 (0.46) GNAO1GNAI3GNAI1GUSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11679158-B2 Biodegradable lipids for the delivery of active agents ALNYLAM PHARMACEUTICALS, INC. (US) 2023-06-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11679158-B2 Biodegradable lipids for the delivery of active agents LIPA, APOB, CETP GNAO1 4378/4885GNAI3 2702/4885GNAI1 2525/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.