Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 15/20 | 0.87 |
| ▸ | CCR3 | P51677 | 2/20 | 0.72 |
| ▸ | DRD4 | P21917 | 3/20 | 0.68 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.68 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.68 |
| ▸ | DRD2 | P14416 | 2/20 | 0.66 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL678856 | 0.87 | MCHR1 (1.00) | MCHR1DRD4 | |
| SCHEMBL678857 | 0.87 | MCHR1 (1.00) | MCHR1DRD4 | |
| SCHEMBL7694199 | 0.86 | DRD2 (0.85) | MCHR1DRD4SLC6A12DRD2SIGMAR1 | |
| SCHEMBL7694198 | 0.86 | DRD2 (0.85) | MCHR1DRD4SLC6A12DRD2SIGMAR1 | |
| SCHEMBL10962511 | 0.85 | MCHR1 (0.64) | MCHR1CCR3DRD4SIGMAR1 | |
| SCHEMBL18841090 | 0.84 | CCR3 (1.00) | MCHR1CCR3DRD4DRD2 | |
| Panuramine SCHEMBL2037759 | 0.84 | MCHR1 (0.83) | MCHR1CCR3DRD4SLC6A12SLC6A13 | |
| Panuramine SCHEMBL9749426 | 0.83 | MCHR1 (0.81) | MCHR1CCR3DRD4SLC6A12SLC6A13 | |
| SCHEMBL9593277 | 0.83 | MCHR1 (0.81) | MCHR1CCR3DRD4SLC6A12SLC6A13 | |
| SCHEMBL9601120 | 0.82 | MCHR1 (0.80) | MCHR1CCR3DRD4SLC6A12SLC6A13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2382975-A2 | Neurogenesis by modulating angiotensin | Braincells, Inc. (US) | 2011-11-02 | — | — | EP | disclosed |