Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 14/20 | 0.85 |
| ▸ | DRD4 | P21917 | 14/20 | 0.85 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.72 |
| ▸ | HTR2A | P28223 | 1/20 | 0.71 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.70 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.70 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.70 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.70 |
| ▸ | TSHR | P16473 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.70 |
| ▸ | NAMPT | P43490 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7694198 | 1.00 | DRD2 (0.85) | DRD2DRD4MCHR1HTR2ATMEM97 | |
| SCHEMBL8706290 | 0.92 | DRD2 (1.00) | DRD2DRD4MCHR1HTR2ATMEM97 | |
| SCHEMBL8707354 | 0.92 | DRD2 (1.00) | DRD2DRD4MCHR1HTR2ATMEM97 | |
| SCHEMBL11555632 | 0.92 | DRD2 (0.82) | DRD2DRD4MCHR1HTR2ATMEM97 | |
| SCHEMBL694949 | 0.92 | SIGMAR1 (0.82) | DRD2DRD4MCHR1TMEM97SIGMAR1 | |
| SCHEMBL2900269 | 0.91 | TMEM97 (0.86) | DRD2DRD4MCHR1HTR2ATMEM97 | |
| SCHEMBL8236258 | 0.91 | TMEM97 (0.86) | DRD2DRD4MCHR1HTR2ATMEM97 | |
| SCHEMBL8738579 | 0.89 | DRD2 (0.77) | DRD2DRD4MCHR1HTR2A | |
| SCHEMBL8709168 | 0.89 | DRD2 (1.00) | DRD2DRD4MCHR1HTR2ASIGMAR1 | |
| SCHEMBL8706273 | 0.89 | DRD2 (0.89) | DRD2DRD4HTR2ANAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-55022699-A | — | — | None | — | — | JP | disclosed |
| WO-2002028829-A2 | PEPTIDE DEFORMYLASE INHIBITORS | QUESTCOR PHARMACEUTICALS, INC. (US) | 2002-04-11 | — | — | WO | disclosed |
| US-4197243-A | ANTIPSYCHOTICS, STRONG CNS DEPRESSANTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1980-04-08 | — | — | US | disclosed |
| JP-S5522699-A | NOVEL 3-AMINO-1-BENZYLPYRROLIDINE DERIVATIVE | YAMANOUCHI PHARMACEUT CO LTD | 1980-02-18 | — | — | JP | disclosed |
| US-4097487-A | CNS DEPRESSANTS, ANTIPSYCHOTICS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JA) | 1978-06-27 | — | — | US | disclosed |