Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.56 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | JAK2 | O60674 | 2/20 | 0.50 |
| ▸ | JAK1 | P23458 | 2/20 | 0.50 |
| ▸ | TYK2 | P29597 | 2/20 | 0.50 |
| ▸ | JAK3 | P52333 | 2/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28090800 | 0.88 | BCAT2 (0.64) | BCAT2ALDH1A1MAPK1LMNAPOLB | |
| SCHEMBL6804476 | 0.87 | CNR2 (0.52) | CNR2KDM4EALDH1A1MAPTL3MBTL1 | |
| SCHEMBL6880915 | 0.86 | LRRK2 (0.52) | BCAT2JAK2JAK1TYK2JAK3 | |
| SCHEMBL27476310 | 0.83 | GRM5 (0.50) | BCAT2JAK2JAK1TYK2JAK3 | |
| SCHEMBL2169026 | 0.82 | CNR2 (0.64) | CNR2JAK2ALDH1A1RAB9ACFTR | |
| SCHEMBL31717616 | 0.81 | PARP1 (0.59) | BCAT2JAK2PARP1KDM4EALDH1A1 | |
| SCHEMBL6126134 | 0.80 | PRKDC (0.56) | JAK2JAK1TYK2JAK3KDM4E | |
| Hydrochloric Acid SCHEMBL31717432 | 0.80 | PARP1 (0.58) | BCAT2JAK2PARP1KDM4EALDH1A1 | |
| SCHEMBL22410906 | 0.79 | AKR1C3 (0.54) | JAK2JAK1TYK2JAK3KDM4E | |
| SCHEMBL30706466 | 0.79 | PDK2 (0.50) | BCAT2CNR2ALDH1A1MAPK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4028133-A1 | RECEPTOR TYROSINE KINASE INHIBITORS FOR TREATMENT OF PROTEIN KINASE MODULATION-RESPONSIVE DISEASE OR DISORDER | The United States of America, as represented by The Secretary, Department of Health and Human Services (US) | 2022-07-20 | — | — | EP | disclosed |
| EP-2382194-A2 | COMPOUNDS FOR THE PREVENTION AND TREATMENT OF CARDIOVASCULAR DISEASE | RESVERLOGIX CORP. (CA) | 2011-11-02 | — | — | EP | disclosed |