Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2554490 | 0.88 | ALOX5 (0.50) | ALOX5LOXL2APEX1MEN1KMT2A | |
| SCHEMBL2565763 | 0.87 | NPC1 (0.52) | ALOX5LOXL2ALDH1A1MAPTRAB9A | |
| SCHEMBL2556350 | 0.87 | ALOX5 (0.47) | ALOX5LOXL2APEX1ALDH1A1MAPT | |
| SCHEMBL2562564 | 0.86 | RAB9A (0.55) | ALOX5LOXL2APEX1ALDH1A1RAB9A | |
| SCHEMBL2560226 | 0.85 | ALOX5 (0.47) | ALOX5LOXL2APEX1MEN1KMT2A | |
| SCHEMBL2563820 | 0.85 | NPC1 (0.50) | ALOX5LOXL2APEX1ALDH1A1MAPT | |
| SCHEMBL2551908 | 0.84 | ALOX5 (0.46) | ALOX5LOXL2APEX1ALDH1A1MAPT | |
| SCHEMBL2564779 | 0.84 | ALOX5 (0.46) | ALOX5LOXL2APEX1ALDH1A1MAPT | |
| SCHEMBL2558639 | 0.83 | DRD2 (0.44) | ALOX5LOXL2ALDH1A1MAPTRAB9A | |
| SCHEMBL2565684 | 0.83 | ALOX5 (0.49) | ALOX5LOXL2KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011121223-A1 | 6-(ALKYL- OR CYCLOALKYL-TRIAZOLOPYRIDAZINE-SULFANYL) BENZOTHIAZOLE DERIVATIVES: PREPARATION, APPLICATION AS MEDICAMENTS AND USE AS MET INHIBITORS | SANOFI-AVENTIS (FR) | 2011-10-06 | — | — | WO | disclosed |