SCHEMBL2565706

SCHEMBL2565706

CCCCCCCCCCCCCC(CCCCC)C1CCCCC1(N=C=O)N=C=O

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5500347 0.90
SCHEMBL29206952 0.69 SIGMAR1 (0.40) SIGMAR1
SCHEMBL19298161 0.68 SHBG (0.39) SIGMAR1
SCHEMBL29322013 0.68 SHBG (0.39) SIGMAR1
SCHEMBL28859417 0.68 SHBG (0.39) SIGMAR1
SCHEMBL475684 0.67
SCHEMBL29109625 0.67 SLC6A4 (0.30)
SCHEMBL7457530 0.66 TSHR (0.38)
SCHEMBL7458659 0.66 TSHR (0.38)
SCHEMBL7453115 0.66 TSHR (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8801918-B2 Point of care heparin determination system MEDTRONIC, INC. (US) 2014-08-12 US disclosed
EP-1747451-B1 POINT OF CARE HEPARIN DETERMINATION SYSTEM MEDTRONIC INC (US) 2011-11-02 EP disclosed
US-20100181210-A1 Point of Care Heparin Determination System QIN WEI 2010-07-22 US disclosed
US-7699966-B2 Point of care heparin determination system MEDTRONIC, INC. (US) 2010-04-20 US disclosed
US-20060016701-A1 Point of care heparin determination system MEDTRONIC, INC. 2006-01-26 US disclosed