Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FADS1 | O60427 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAOB | P27338 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | ADK | P55263 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25168158 | 0.85 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1HPGDHTT | |
| SCHEMBL1057155 | 0.82 | ALDH1A1 (0.55) | ALDH1A1KMT2AMEN1ADKHPGD | |
| SCHEMBL7106401 | 0.73 | ALDH1A1 (0.73) | FADS1ALDH1A1MAOBKMT2AMEN1 | |
| SCHEMBL10615344 | 0.70 | DDB1 (0.36) | FADS1ALDH1A1KMT2AHTT | |
| SCHEMBL10480576 | 0.68 | ALDH1A1 (0.40) | ALDH1A1MAOBKMT2AMEN1CYP19A1 | |
| SCHEMBL7030920 | 0.67 | ALDH1A1 (0.43) | FADS1ALDH1A1MAOBGSK3BHTT | |
| SCHEMBL17962600 | 0.66 | ALDH1A1 (0.47) | ALDH1A1KMT2AMEN1TDP1 | |
| SCHEMBL17501668 | 0.66 | NR3C1 (0.42) | FADS1ALDH1A1MAOBGSK3B | |
| SCHEMBL11287657 | 0.66 | MDM2 (0.48) | FADS1MDM2EPHX1 | |
| SCHEMBL174752 | 0.65 | MAOB (0.36) | FADS1MAOBKMT2ACYP19A1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118265697-A | Novel process for preparing 5-hydroxy-5-aryl-pyrrol-2-ones and intermediates therefor | 平博维斯伯生命科学有限公司 | 2024-06-28 | — | — | CN | claimed |
| CN-118265697-A | Novel process for preparing 5-hydroxy-5-aryl-pyrrol-2-ones and intermediates therefor | 平博维斯伯生命科学有限公司 | 2024-06-28 | — | — | CN | disclosed |
| WO-2023079538-A1 | A NOVEL PROCESS FOR PREPARATION OF 5-HYDROXY-5-ARYL-PYRROL-2-ONES AND THEIR INTERMEDIATES | PNB VESPER LIFE SCIENCE PVT LIMITED (IN) | 2023-05-11 | — | — | WO | disclosed |
| WO-2023079538-A1 | A NOVEL PROCESS FOR PREPARATION OF 5-HYDROXY-5-ARYL-PYRROL-2-ONES AND THEIR INTERMEDIATES | PNB VESPER LIFE SCIENCE PVT LIMITED (IN) | 2023-05-11 | — | — | WO | disclosed |