Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.32 |
| ▸ | MME | P08473 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31522775 | 1.00 | POLB (0.35) | POLBSMN1; SMN2TAS1R3TAS1R1NOS3 | |
| Trifluoroacetic Acid SCHEMBL30878141 | 0.89 | PDF (0.34) | POLBNOS3NOS1NOS2MME | |
| SCHEMBL8294718 | 0.81 | TAS1R3 (0.36) | POLBSMN1; SMN2TAS1R3TAS1R1NOS3 | |
| SCHEMBL7159426 | 0.80 | TAS1R3 (0.49) | POLBSMN1; SMN2TAS1R3TAS1R1NOS3 | |
| SCHEMBL14609391 | 0.80 | TAS1R3 (0.49) | POLBSMN1; SMN2TAS1R3TAS1R1NOS3 | |
| SCHEMBL8297645 | 0.80 | TAS1R3 (0.49) | POLBSMN1; SMN2TAS1R3TAS1R1NOS3 | |
| Hydrochloric Acid SCHEMBL28418638 | 0.78 | TAS1R3 (0.47) | POLBSMN1; SMN2TAS1R3TAS1R1NOS3 | |
| Hydrochloric Acid SCHEMBL28418639 | 0.78 | TAS1R3 (0.47) | POLBSMN1; SMN2TAS1R3TAS1R1NOS3 | |
| SCHEMBL13127847 | 0.77 | KISS1R (0.31) | — | |
| SCHEMBL10679659 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230151060-A1 | CYCLIC PEPTIDE COMPOUND HAVING KRAS INHIBITORY ACTION | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230151060-A1 | CYCLIC PEPTIDE COMPOUND HAVING KRAS INHIBITORY ACTION | KRAS, NRAS, HRAS | POLB 3546/4885SMN1; SMN2 4201/4885TAS1R3 2657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.