Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 1.00 |
| ▸ | MAOB | P27338 | 3/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 12/20 | 0.60 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | ALPL | P05186 | 1/20 | 0.50 |
| ▸ | ALPI | P09923 | 1/20 | 0.50 |
| ▸ | ALPG | P10696 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL407009 | 1.00 | MAOA (1.00) | MAOAMAOBALDH1A1TSHRMAPK1 | |
| SCHEMBL407010 | 1.00 | MAOA (1.00) | MAOAMAOBALDH1A1TSHRMAPK1 | |
| SCHEMBL29351256 | 1.00 | MAOA (1.00) | MAOAMAOBALDH1A1TSHRMAPK1 | |
| Bromide SCHEMBL27643162 | 0.98 | MAOA (0.97) | MAOAMAOBALDH1A1TSHRMAPK1 | |
| SCHEMBL20865430 | 0.80 | MAOA (0.71) | MAOAMAOBALDH1A1TDP1KCNH2 | |
| SCHEMBL670018 | 0.79 | MAOA (1.00) | MAOAMAOBALDH1A1TDP1KCNH2 | |
| SCHEMBL670019 | 0.79 | MAOA (1.00) | MAOAMAOBALDH1A1TDP1KCNH2 | |
| SCHEMBL2561900 | 0.77 | MAOA (0.96) | MAOAMAOBALDH1A1TDP1KCNH2 | |
| SCHEMBL2561898 | 0.77 | MAOA (0.96) | MAOAMAOBALDH1A1TDP1KCNH2 | |
| SCHEMBL4961652 | 0.77 | MAOA (0.62) | MAOAMAOBKCNH2RIOK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2336248-A1 | Dying composition comprising a particular disulfide dye and process of dying keratinous fibres with this dye | L'Oréal (FR) | 2011-06-22 | — | — | EP | disclosed |
| EP-2333018-A1 | Dying composition comprising a particular disulfide dye and process of dying keratinous fibres with this dye | L'Oréal (FR) | 2011-06-15 | — | — | EP | disclosed |
| EP-2330160-A1 | Dying composition comprising a particular disulfide dye and process of dying keratinous fibres with this dye | L'Oréal (FR) | 2011-06-08 | — | — | EP | disclosed |
| EP-1647580-B1 | Dying composition comprising a particular disulfide dye and process of dying keratinous fibres with this dye. | OREAL (FR) | 2011-02-16 | — | — | EP | disclosed |
| US-7488354-B2 | Dyeing composition comprising at least one disulphide dye and method of dyeing human keratin fibers using this dye | L'OREAL S.A. (FR) | 2009-02-10 | — | — | US | disclosed |
| US-20060080791-A1 | Dyeing composition comprising at least one disulphide dye and method of dyeing human keratin fibers using this dye | L'OREAL S.A. (FR) | 2006-04-20 | — | — | US | disclosed |
| EP-1647580-A1 | Dying composition comprising a particular disulfide dye and process of dying keratinous fibres with this dye. | L'OREAL (FR) | 2006-04-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060080791-A1 | Dyeing composition comprising at least one disulphide dye and method of dyeing human keratin fibers using this dye | KRT18, DSG1, DSC1 | MAOA 2442/4885MAOB 2550/4885ALDH1A1 1195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.