SCHEMBL25658409

SCHEMBL25658409

N#Cc1ccc(-c2cc(F)c(F)c(C#N)c2)c(C(F)(F)F)c1

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 2/20 0.50
AR P10275 11/20 0.41
TRPV4 Q9HBA0 2/20 0.41
PDE3B Q13370 1/20 0.37
PDE3A Q14432 1/20 0.37
ALOX5AP P20292 1/20 0.36
FEN1 P39748 1/20 0.36
PGR P06401 1/20 0.36
KDM1A O60341 1/20 0.36
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35
CYP11B1 P15538 1/20 0.35
CYP11B2 P19099 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20111536 0.86 ALOX5AP (0.47) KIF11ARPDE3BPDE3AALOX5AP
SCHEMBL25658384 0.84 KIF11 (0.54) KIF11ARTRPV4PDE3BPDE3A
SCHEMBL20616789 0.82 AR (0.61) KIF11ARALOX5APFEN1PGR
SCHEMBL28668535 0.78 KIF11 (0.57) KIF11ARTRPV4PGRCYP11B2
SCHEMBL25658407 0.78 KIF11 (0.46) KIF11ARTRPV4PGR
SCHEMBL7604551 0.78 TRPV4 (0.56) KIF11ARTRPV4
SCHEMBL17955138 0.77 KIF11 (0.53) KIF11ARTRPV4PDE3BPDE3A
SCHEMBL25658402 0.77 KIF11 (0.45) KIF11ARTRPV4PGR
SCHEMBL25658487 0.77 FEN1 (0.57) KIF11ARALOX5APFEN1ESR1
SCHEMBL2371259 0.75 AR (0.47) KIF11ARTRPV4PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11825743-B2 Organic molecules for use in organic optoelectronic devices SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-21 US disclosed
EP-3585777-B1 ORGANIC MOLECULES, ESPECIALLY FOR USE IN ORGANIC OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO LTD (KR) 2023-05-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11825743-B2 Organic molecules for use in organic optoelectronic devices OR10J3, OR51E2, OCIAD2 KIF11 3288/4885AR 4630/4885TRPV4 243/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.