SCHEMBL20111536

SCHEMBL20111536

N#Cc1cc(-c2ccc(C(F)(F)F)cc2C(F)(F)F)cc(F)c1F

nearest known ligand 0.47

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALOX5AP P20292 2/20 0.47
FEN1 P39748 2/20 0.47
AR P10275 14/20 0.43
CYP11B1 P15538 1/20 0.41
CYP11B2 P19099 1/20 0.41
KIF11 P52732 2/20 0.40
PDE3B Q13370 1/20 0.37
PDE3A Q14432 1/20 0.37
PGR P06401 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25658487 0.88 FEN1 (0.57) ALOX5APFEN1ARCYP11B1CYP11B2
SCHEMBL25658409 0.86 KIF11 (0.50) ALOX5APFEN1ARCYP11B1CYP11B2
SCHEMBL20111587 0.84 ALOX5AP (0.47) ALOX5APFEN1ARCYP11B1CYP11B2
SCHEMBL20616789 0.82 AR (0.61) ALOX5APFEN1ARCYP11B1CYP11B2
SCHEMBL20111535 0.78 AR (0.46) ALOX5APFEN1ARCYP11B1CYP11B2
SCHEMBL19903462 0.77 CYP11B1 (0.48) ALOX5APFEN1ARCYP11B1CYP11B2
SCHEMBL20111586 0.77 AR (0.45) ALOX5APFEN1ARCYP11B1CYP11B2
SCHEMBL21898833 0.75 AR (0.46) ARCYP11B1CYP11B2KIF11PGR
SCHEMBL25658426 0.75 ALOX5AP (0.55) ALOX5APFEN1ARCYP11B1CYP11B2
SCHEMBL1360894 0.74 KIF11 (0.62) ALOX5APFEN1ARCYP11B2KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10971688-B2 Organic molecules for use in organic optoelectronic devices CYNORA GMBH (DE) 2021-04-06 US disclosed
US-20190248741-A1 ORGANIC MOLECULES FOR USE IN ORGANIC OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2019-08-15 US disclosed
EP-3360945-B1 ORGANIC ELECTROLUMINESCENT DEVICE CYNORA GMBH (DE) 2019-04-24 EP disclosed
WO-2018077492-A1 ORGANIC MOLECULES, ESPECIALLY FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2018-05-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10971688-B2 Organic molecules for use in organic optoelectronic devices OR10J3, OR51E2, OPRM1 ALOX5AP 2592/4885FEN1 1121/4885AR 4611/4885
US-20190248741-A1 ORGANIC MOLECULES FOR USE IN ORGANIC OPTOELECTRONIC DEVICES OR10J3, ORC3, AOC3 ALOX5AP 3253/4885FEN1 1286/4885AR 4386/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.