Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.79 |
| ▸ | CA1 | P00915 | 5/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA9 | Q16790 | 3/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | AGXT | P21549 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrogen Peroxide SCHEMBL28758135 | 0.92 | TSHR (0.94) | TSHRCA1CA2CA9CA7 | |
| SCHEMBL27380 | 0.89 | TSHR (1.00) | TSHRCA1CA2CA9CA7 | |
| SCHEMBL5311581 | 0.89 | TSHR (1.00) | TSHRCA1CA2CA9CA7 | |
| Hydroxyamine SCHEMBL1680424 | 0.86 | TSHR (0.83) | TSHRCA1CA2CA9CA7 | |
| SCHEMBL28758137 | 0.86 | TSHR (0.83) | TSHRCA1CA2CA9CA7 | |
| SCHEMBL7243519 | 0.86 | TSHR (0.83) | TSHRCA1CA2CA9CA7 | |
| SCHEMBL1009266 | 0.86 | TSHR (0.94) | TSHRCA1CA2CA9CA7 | |
| SCHEMBL10317949 | 0.86 | TSHR (0.94) | TSHRCA1CA2CA9CA7 | |
| SCHEMBL9795394 | 0.86 | TSHR (0.94) | TSHRCA1CA2CA9CA7 | |
| SCHEMBL9491202 | 0.86 | TSHR (0.94) | TSHRCA1CA2CA9CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130315829-A1 | Compounds and Methods for Detecting Reactive Oxygen Species | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-11-28 | — | — | US | disclosed |
| WO-2011133800-A1 | COMPOUNDS AND METHODS FOR DETECTING REACTIVE OXYGEN SPECIES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-10-27 | — | — | WO | disclosed |
| US-20070231467-A1 | METHOD FOR MANUFACTURING LIGHT EMITTING DEVICE AND METHOD FOR MANUFACTURING ELECTRONIC APPARATUS | SEIKO EPSON CORPORATION (JP) | 2007-10-04 | — | — | US | disclosed |
| US-20070218190-A1 | METHOD FOR MANUFACTURING LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC APPARATUS | SEIKO EPSON CORPORATION (JP) | 2007-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130315829-A1 | Compounds and Methods for Detecting Reactive Oxygen Species | GPX4, TXN2, PRDX5 | TSHR 4845/4885CA1 1003/4885CA2 450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.