Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | XBP1 | P17861 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | CES2 | O00748 | 3/20 | 0.43 |
| ▸ | CES1 | P23141 | 3/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3289274 | 1.00 | ALDH1A1 (0.51) | ALDH1A1MAPTRAB9ALMNAMAPK1 | |
| SCHEMBL2566020 | 1.00 | ALDH1A1 (0.51) | ALDH1A1MAPTRAB9ALMNAMAPK1 | |
| SCHEMBL11640891 | 0.89 | SMN1; SMN2 (0.53) | ALDH1A1MAPTRAB9ALMNAMAPK1 | |
| SCHEMBL11640894 | 0.89 | SMN1; SMN2 (0.53) | ALDH1A1MAPTRAB9ALMNAMAPK1 | |
| SCHEMBL28420371 | 0.88 | ALDH1A1 (0.51) | ALDH1A1MAPTRAB9ALMNAMAPK1 | |
| SCHEMBL28892760 | 0.86 | ALDH1A1 (0.64) | ALDH1A1MAPTRAB9ALMNAMAPK1 | |
| SCHEMBL29119462 | 0.86 | TSHR (0.46) | ALDH1A1MAPTRAB9ALMNAMAPK1 | |
| SCHEMBL16534386 | 0.85 | SLC16A3 (0.43) | ALDH1A1MAPTRAB9ALMNAMAPK1 | |
| SCHEMBL16534389 | 0.85 | SLC16A3 (0.43) | ALDH1A1MAPTRAB9ALMNAMAPK1 | |
| SCHEMBL9447417 | 0.85 | ALDH1A1 (0.47) | ALDH1A1MAPTRAB9ALMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210324344-A1 | ENONE REDUCTASES | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2021-10-21 | — | — | US | disclosed |
| US-10995321-B2 | Enone reductases | CODEXIS, INC. (US) | 2021-05-04 | — | — | US | disclosed |
| US-20200040311-A1 | ENONE REDUCTASES | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2020-02-06 | — | — | US | disclosed |
| US-20180312815-A1 | ENONE REDUCTASES | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2018-11-01 | — | — | US | disclosed |
| CN-108484849-A | A kind of block type ionomer antistatic agent and preparation method thereof | 湖南辰砾新材料有限公司 | 2018-09-04 | — | — | CN | disclosed |
| US-10035988-B2 | Enone reductases | CODEXIS, INC. (US) | 2018-07-31 | — | — | US | disclosed |
| US-20170175087-A1 | ENONE REDUCTASES | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2017-06-22 | — | — | US | disclosed |
| US-9617568-B2 | Enone reductases | CODEXIS, INC. (US) | 2017-04-11 | — | — | US | disclosed |
| US-20160273007-A1 | ENONE REDUCTASES | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2016-09-22 | — | — | US | disclosed |
| US-9388438-B2 | Enone reductases | CODEXIS, INC. (US) | 2016-07-12 | — | — | US | disclosed |
| US-7718096-B2 | Stabilized electrochromic media | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-05-18 | — | — | US | disclosed |
| US-7595011-B2 | One or more solvents, one or more materials which are functional elements of electrochromic devices, one or more ultraviolet light absorbers selected from hydroxyphenylbenzotriazoles and tris-aryl-s-triazines, and one or more NH or N-alkyl hindered amine light stabilizers; discoloration inhibition | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2009-09-29 | — | — | US | disclosed |
| EP-1896550-A1 | STABILIZED ELECTROCHROMIC MEDIA | Ciba Specialty Chemicals Holding Inc. (CH) | 2008-03-12 | — | — | EP | disclosed |
| EP-1789842-A1 | STABILIZED ELECTROCHROMIC MEDIA | CIBA SPECIALTY CHEMICALS HOLDING INC. Patent Departement (CH) | 2007-05-30 | — | — | EP | disclosed |
| WO-2007003508-A1 | STABILIZED ELECTROCHROMIC MEDIA | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2007-01-11 | — | — | WO | disclosed |
| US-20070002423-A1 | Stabilized electrochromic media | CIBA SPECIALTY CHEMICALS CORP. | 2007-01-04 | — | — | US | disclosed |
| WO-2006005691-A1 | STABILIZED ELECTROCHROMIC MEDIA | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2006-01-19 | — | — | WO | disclosed |
| US-20060007519-A1 | Stabilized electrochromic media | CIBA SPECIALTY CHEMICALS CORP. | 2006-01-12 | — | — | US | disclosed |
| US-6365311-B1 | THERMAL STABILITY; LOW COLOR; ABSENCE OF ENVIRONMENTALLY UNDESIRABLE TOXIC METALS; POLYETHERIFIED BISPHENOL A FUMARATE BINDER; POLYSILOXANE COATED STRONTIUM FERRITE CARRIER | EASTMAN KODAK COMPANY | 2002-04-02 | — | — | US | disclosed |
| US-5266718-A | Antidiabetic agents | ADIR ET COMPAGNIE (FR) | 1993-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180312815-A1 | ENONE REDUCTASES | ENO1, DCXR, RRM2B | ALDH1A1 1267/4885MAPT 4492/4885RAB9A 3233/4885 |
| US-10995321-B2 | Enone reductases | ENO1, DCXR, RRM2B | ALDH1A1 1267/4885MAPT 4492/4885RAB9A 3233/4885 |
| US-20200040311-A1 | ENONE REDUCTASES | ENO1, DCXR, RRM2B | ALDH1A1 1267/4885MAPT 4492/4885RAB9A 3233/4885 |
| US-20210324344-A1 | ENONE REDUCTASES | ENO1, DCXR, RRM2B | ALDH1A1 1267/4885MAPT 4492/4885RAB9A 3233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.