SCHEMBL25660281

SCHEMBL25660281

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccccc3-n3c4ccccc4c4ccc5oc6ccccc6c5c43)n2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.33
ALDH1A1 P00352 6/20 0.33
TSHR P16473 5/20 0.33
HPGD P15428 2/20 0.33
DUSP3 P51452 1/20 0.32
ADORA3 P0DMS8 1/20 0.32
ALOX15 P16050 1/20 0.32
ADORA2A P29274 1/20 0.32
ADORA2B P29275 1/20 0.32
ADORA1 P30542 1/20 0.32
LMNA P02545 5/20 0.31
KDM4E B2RXH2 4/20 0.31
HSD17B10 Q99714 3/20 0.31
MAPK1 P28482 2/20 0.31
POLB P06746 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
KMT2A Q03164 2/20 0.31
TP53 P04637 1/20 0.31
NFKB1 P19838 1/20 0.31
NFKB2 Q00653 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24218073 0.98 MAPT (0.32) MAPTALDH1A1TSHRHPGDDUSP3
SCHEMBL24218122 0.97 DUSP3 (0.32) MAPTALDH1A1TSHRHPGDDUSP3
SCHEMBL25660286 0.95 PLA2G2A (0.32) MAPTALDH1A1TSHRHPGDDUSP3
SCHEMBL24218182 0.92 DUSP3 (0.32) MAPTALDH1A1TSHRHPGDDUSP3
SCHEMBL24417288 0.91 PLA2G2A (0.34) L3MBTL1
SCHEMBL24417287 0.91 PRKDC (0.33) L3MBTL1
SCHEMBL24025163 0.91 MAPT (0.32) MAPTALDH1A1TSHRHPGDLMNA
SCHEMBL24839189 0.91 DUSP3 (0.33) ALDH1A1DUSP3LMNASMN1; SMN2TDP1
SCHEMBL27324466 0.90 PLA2G2A (0.36) MAPTALDH1A1TSHRHPGDL3MBTL1
SCHEMBL24025263 0.90 PLA2G2A (0.32) MAPTALDH1A1TSHRHPGDLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230276690-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-08-31 US disclosed
US-20230157156-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2023-05-18 US disclosed
US-20230157156-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2023-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230276690-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME L1CAM, TELO2, LIMS1 MAPT 2197/4885ALDH1A1 149/4885TSHR 4584/4885
US-20230157156-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME OR10J3, VDAC2, ICOSLG MAPT 1032/4885ALDH1A1 604/4885TSHR 4702/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.