SCHEMBL25660286

SCHEMBL25660286

c1ccc(-c2cccc(-c3nc(-c4ccccc4)nc(-c4ccccc4-n4c5ccccc5c5ccc6oc7ccccc7c6c54)n3)c2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 3/20 0.32
PLA2G4A P47712 3/20 0.32
PLA2G10 O15496 1/20 0.32
PRKDC P78527 1/20 0.31
DUSP3 P51452 1/20 0.31
ALDH1A1 P00352 2/20 0.31
HPGD P15428 2/20 0.31
TSHR P16473 2/20 0.31
MAPT P10636 2/20 0.31
KDM4E B2RXH2 1/20 0.30
TP53 P04637 1/20 0.30
NFKB1 P19838 1/20 0.30
MAPK1 P28482 1/20 0.30
NFKB2 Q00653 1/20 0.30
RELA Q04206 1/20 0.30
ATM Q13315 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
HSD17B10 Q99714 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24218073 0.95 MAPT (0.32) PLA2G2APLA2G4ADUSP3ALDH1A1HPGD
SCHEMBL25660281 0.95 MAPT (0.33) DUSP3ALDH1A1HPGDTSHRMAPT
SCHEMBL24218182 0.94 DUSP3 (0.32) PLA2G2APLA2G4APLA2G10DUSP3ALDH1A1
SCHEMBL24218122 0.94 DUSP3 (0.32) DUSP3ALDH1A1HPGDTSHRMAPT
SCHEMBL24025307 0.93 PLA2G2A (0.34) PLA2G2APLA2G4APLA2G10PRKDCALDH1A1
SCHEMBL22514626 0.93 PLA2G2A (0.34) PLA2G2APLA2G4APLA2G10PRKDCALDH1A1
SCHEMBL24417288 0.93 PLA2G2A (0.34) PLA2G2APLA2G4APLA2G10PRKDCL3MBTL1
SCHEMBL24417287 0.93 PRKDC (0.33) PRKDCL3MBTL1
SCHEMBL27324466 0.92 PLA2G2A (0.36) PLA2G2APLA2G4APLA2G10PRKDCALDH1A1
SCHEMBL24417237 0.91 PRKDC (0.33) PRKDCALDH1A1TSHRMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230276690-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-08-31 US disclosed
US-20230276690-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-08-31 US disclosed
US-20230157156-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2023-05-18 US disclosed
US-20230157156-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2023-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230276690-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME L1CAM, TELO2, LIMS1 PLA2G2A 2820/4885PLA2G4A 3775/4885PLA2G10 2818/4885
US-20230157156-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME OR10J3, VDAC2, ICOSLG PLA2G2A 2557/4885PLA2G4A 3003/4885PLA2G10 2525/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.