SCHEMBL25660770

SCHEMBL25660770

CNC(Cc1cn(C)c2ccccc12)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.55
ADAM17 P78536 1/20 0.54
MMP9 P14780 1/20 0.52
MMP8 P22894 1/20 0.52
KDM4E B2RXH2 4/20 0.51
HPGD P15428 1/20 0.50
HSD17B10 Q99714 1/20 0.50
CMA1 P23946 3/20 0.49
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
ALDH1A1 P00352 1/20 0.48
LMNA P02545 1/20 0.48
MAPT P10636 1/20 0.48
SMYD3 Q9H7B4 1/20 0.48
POLB P06746 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31158207 1.00 GPR84 (0.55) GPR84ADAM17MMP9MMP8KDM4E
SCHEMBL14035189 1.00 GPR84 (0.55) GPR84ADAM17MMP9MMP8KDM4E
SCHEMBL14011134 1.00 GPR84 (0.55) GPR84ADAM17MMP9MMP8KDM4E
SCHEMBL22413974 0.89 ADAM17 (0.54) GPR84ADAM17MMP9MMP8KDM4E
SCHEMBL28163927 0.89 ADAM17 (0.54) GPR84ADAM17MMP9MMP8KDM4E
SCHEMBL14537108 0.89 GPR84 (0.55) GPR84ADAM17MMP9MMP8KDM4E
SCHEMBL20342076 0.89 GPR84 (0.55) GPR84ADAM17MMP9MMP8KDM4E
SCHEMBL24719041 0.86 ADAM17 (0.53) GPR84ADAM17MMP9MMP8KDM4E
SCHEMBL22521341 0.86 ADAM17 (0.53) GPR84ADAM17MMP9MMP8KDM4E
SCHEMBL13033620 0.86 GPR84 (0.53) GPR84ADAM17MMP9MMP8KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4724459-A1 PEPTIDE COMPOSITIONS TARGETING GLYPICAN-3 AND USES THEREOF Peptidream Inc (JP) 2026-04-15 EP disclosed
EP-4724457-A2 RADIOPHARMACEUTICAL COMPOSITIONS TARGETING GLYPICAN-3 AND USES THEREOF Rayzebio, Inc. (US) 2026-04-15 EP disclosed
WO-2024254339-A9 RADIOPHARMACEUTICAL COMPOSITIONS TARGETING GLYPICAN-3 AND USES THEREOF RAYZEBIO, INC. (US) 2025-10-16 WO disclosed
WO-2024254339-A2 RADIOPHARMACEUTICAL COMPOSITIONS TARGETING GLYPICAN-3 AND USES THEREOF RAYZEBIO, INC. (US) 2024-12-12 WO disclosed
WO-2024252336-A1 PEPTIDE COMPOSITIONS TARGETING GLYPICAN-3 AND USES THEREOF PEPTIDREAM INC. (JP) 2024-12-12 WO disclosed
CN-111004167-B Salts and prodrugs of 1-methyl-D-tryptophan 新联基因公司 2024-03-22 CN disclosed
US-20230158179-A1 RADIOPHARMACEUTICAL CONJUGATE COMPOSITIONS AND USES THEREOF RAYZEBIO, INC. 2023-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230158179-A1 RADIOPHARMACEUTICAL CONJUGATE COMPOSITIONS AND USES THEREOF PAICS, LNPEP, DNPEP GPR84 1039/4885ADAM17 551/4885MMP9 3717/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.