Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 7/20 | 0.65 |
| ▸ | CHRM2 known ✓ | P08172 | 2/20 | 0.65 |
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 0.65 |
| ▸ | CHRM4 known ✓ | P08173 | 1/20 | 0.65 |
| ▸ | CHRM5 known ✓ | P08912 | 1/20 | 0.65 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.65 |
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.61 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.65 |
| ▸ | RAD52 | P43351 | 2/20 | 0.65 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.65 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.65 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.65 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.65 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | EGFR | P00533 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.65 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL97814 | 0.97 | — | — | |
| Fluoride Ion SCHEMBL29006338 | 0.94 | ACHE (0.61) | ACHEHSP90AA1RAD52CHRM2ADRA2A | |
| Iodide SCHEMBL28632768 | 0.94 | CHRM2 (0.61) | ACHEHSP90AA1RAD52CHRM2ADRA2A | |
| Hydrochloric Acid SCHEMBL558078 | 0.94 | KMT2A (0.65) | ACHEHSP90AA1RAD52CHRM2ADRA2A | |
| Iodide SCHEMBL5091338 | 0.94 | CHRM2 (0.61) | ACHEHSP90AA1RAD52CHRM2ADRA2A | |
| Bromide SCHEMBL28311092 | 0.88 | ACHE (0.54) | ACHEHSP90AA1RAD52CHRM2ADRA2A | |
| SCHEMBL28014212 | 0.87 | ACHE (0.54) | ACHEHSP90AA1RAD52CHRM2ADRA2A | |
| SCHEMBL1072280 | 0.87 | ACHE (0.54) | ACHEHSP90AA1RAD52CHRM2ADRA2A | |
| Hydrochloric Acid SCHEMBL11621756 | 0.85 | KMT2A (0.56) | ACHEHSP90AA1RAD52CHRM2ADRA2A | |
| SCHEMBL29883354 | 0.85 | ACHE (0.52) | ACHEHSP90AA1RAD52CHRM2ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114436286-B | Molecular sieve with TON structure and preparation method and application thereof | 中国石油化工股份有限公司 | 2023-08-29 | — | — | CN | claimed |
| CN-114436286-A | Molecular sieve with TON structure and preparation method and application thereof | 中国石油化工股份有限公司 | 2022-05-06 | — | — | CN | claimed |
| CN-111825102-B | Dry glue conversion synthesis method of high-silicon Y molecular sieve | 中国科学院大连化学物理研究所 | 2022-03-22 | — | — | CN | claimed |
| EP-0877298-B1 | Coated xerographic photographic paper | XEROX CORP (US) | 2001-08-29 | — | — | EP | claimed |
| US-6210816-B1 | Translucent xerographic recording substrates | XEROX CORPORATION | 2001-04-03 | — | — | US | claimed |
| US-5908723-A | Recording sheets | XEROX CORPORATION (US) | 1999-06-01 | — | — | US | claimed |
| US-5846637-A | Coated xerographic photographic paper | XEROX CORPORATION (US) | 1998-12-08 | — | — | US | claimed |
| EP-0877298-A2 | Coated xerographic photographic paper | Xerox Corporation (US) | 1998-11-11 | — | — | EP | claimed |
| US-20240182404-A1 | INHIBITOR FOR RuO4 GAS GENERATION AND METHOD FOR INHIBITING RuO4 GAS GENERATION | TOKUYAMA CORPORATION (JP) | 2024-06-06 | — | — | US | disclosed |
| US-11932590-B2 | Inhibitor for RuO4 gas generation and method for inhibiting RuO4 gas generation | TOKUYAMA CORPORATION (JP) | 2024-03-19 | — | — | US | disclosed |
| CN-114514598-A | RuO4Gas generation inhibitor and RuO4Method for suppressing gas generation | 株式会社德山 | 2022-05-17 | — | — | CN | disclosed |
| CN-114436286-A | Molecular sieve with TON structure and preparation method and application thereof | 中国石油化工股份有限公司 | 2022-05-06 | — | — | CN | disclosed |
| US-20210340095-A1 | INHIBITOR FOR RuO4 GAS GENERATION AND METHOD FOR INHIBITING RuO4 GAS GENERATION | TOKUYAMA CORPORATION (JP) | 2021-11-04 | — | — | US | disclosed |
| EP-3080859-B1 | NA BASED SECONDARY BATTERY | FIELD UPGRADING USA (US) | 2020-04-08 | — | — | EP | disclosed |
| EP-0541631-A1 | N-SUBSTITUTED PYRIDINIUMBORATES | EASTMAN KODAK COMPANY (US) | 1993-05-19 | — | — | EP | disclosed |
| US-5175352-A | PROCESS FOR PREPARING 2,6-NAPHTHALENEDICARBOXYLIC ACID | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1992-12-29 | — | — | US | disclosed |
| EP-0496264-A2 | Process for preparing 2,6-naphthalenedicarboxylic acid | Mitsubishi Chemical Corporation (JP) | 1992-07-29 | — | — | EP | disclosed |
| WO-1992002504-A1 | N-SUBSTITUTED PYRIDINIUMBORATES | EASTMAN KODAK COMPANY (US) | 1992-02-20 | — | — | WO | disclosed |
| US-5075190-A | Heat and humidity resistant | EASTMAN KODAK COMPANY (US) | 1991-12-24 | — | — | US | disclosed |
| US-4228230-A | Ultrasonic imaging of internally fogged silver halide elements | EASTMAN KODAK COMPANY (US) | 1980-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11932590-B2 | Inhibitor for RuO4 gas generation and method for inhibiting RuO4 gas generation | RUVBL2, RUVBL1, LEO1 | ACHE 909/4885CHRM2 2379/4885CHRM1 1985/4885 |
| US-20240182404-A1 | INHIBITOR FOR RuO4 GAS GENERATION AND METHOD FOR INHIBITING RuO4 GAS GENERATION | RUVBL2, RUVBL1, LEO1 | ACHE 909/4885CHRM2 2379/4885CHRM1 1985/4885 |
| US-20210340095-A1 | INHIBITOR FOR RuO4 GAS GENERATION AND METHOD FOR INHIBITING RuO4 GAS GENERATION | RUVBL2, RUVBL1, LEO1 | ACHE 909/4885CHRM2 2379/4885CHRM1 1985/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.