Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 11/20 | 0.47 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | GPR4 | P46093 | 2/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.37 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2228524 | 0.79 | CTSK (0.50) | CTSKKMOGPR4FGFR4MAPK1 | |
| SCHEMBL2227354 | 0.78 | CTSK (0.53) | CTSKKMOGPR4HRH4FGFR4 | |
| SCHEMBL3316538 | 0.76 | CTSK (0.45) | CTSKKMOGPR4HRH4FGFR4 | |
| SCHEMBL16922207 | 0.72 | KMO (0.40) | CTSKKMOGPR4F2LMNA | |
| SCHEMBL8269410 | 0.72 | CTSK (0.39) | CTSKGPR4HRH4FGFR4CTSS | |
| SCHEMBL8269960 | 0.70 | CTSK (0.51) | CTSKGPR4FGFR4LMNAHTT | |
| SCHEMBL3315262 | 0.69 | CTSK (0.61) | CTSKKMOGPR4HRH4FGFR4 | |
| SCHEMBL5792575 | 0.69 | CTSK (0.44) | CTSKGPR4FGFR4CTSS | |
| SCHEMBL109350 | 0.69 | — | — | |
| SCHEMBL30362276 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2382240-A2 | POLYMERS FUNCTIONALIZED WITH NITRILE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP | Bridgestone Corporation (JP) | 2011-11-02 | — | — | EP | disclosed |
| WO-2010085622-A9 | POLYMERS FUNCTIONALIZED WITH NITRILE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP | BRIDGESTONE CORPORATION (JP) | 2010-12-23 | — | — | WO | disclosed |
| WO-2010085622-A2 | POLYMERS FUNCTIONALIZED WITH NITRILE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP | BRIDGESTONE CORPORATION (JP) | 2010-07-29 | — | — | WO | disclosed |