Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | MMP12 | P39900 | 2/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | PREP | P48147 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25666189 | 0.90 | MMP1 (0.45) | MMP1MMP2MMP9MMP12MRGPRX4 | |
| SCHEMBL25666154 | 0.90 | MMP1 (0.39) | MMP1MMP2MMP9MMP12HPGDS | |
| SCHEMBL99439 | 0.85 | HPGDS (0.44) | MMP1MMP2MMP9MMP12HPGDS | |
| SCHEMBL25666240 | 0.84 | MMP1 (0.38) | MMP1MMP2MMP9MMP12HPGDS | |
| SCHEMBL25666179 | 0.83 | HPGDS (0.40) | MMP1MMP2MMP9MMP12HPGDS | |
| SCHEMBL102846 | 0.81 | HPGDS (0.43) | MMP1MMP9HPGDSADRB2ADRB1 | |
| SCHEMBL25666205 | 0.81 | MMP1 (0.42) | MMP1MMP2MMP9MMP12HPGDS | |
| SCHEMBL20285585 | 0.78 | HPGDS (0.44) | HPGDSGSK3BPTPN1 | |
| SCHEMBL13617611 | 0.77 | HPGDS (0.42) | MMP1MMP9MMP12HPGDSMEN1 | |
| SCHEMBL18993738 | 0.76 | SMN1; SMN2 (0.41) | MMP1MMP2MMP9MMP12MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023077678-A1 | SMALL MOLECULE COMPOUND TARGETING SRSF6 PROTEIN AND PREPARATION METHOD THEREFOR AND USE THEREOF | 中国药科大学 | 2023-05-11 | — | — | WO | disclosed |