Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25666221 | 0.90 | MMP1 (0.40) | MMP1MMP2MMP9MMP12PPARG | |
| SCHEMBL25666179 | 0.89 | HPGDS (0.40) | MMP1MMP2MMP9MMP12KMT2A | |
| SCHEMBL99439 | 0.88 | HPGDS (0.44) | MMP1MMP2MMP9MMP12RAB9A | |
| SCHEMBL25666189 | 0.87 | MMP1 (0.45) | MMP1MMP2MMP9MMP12KMT2A | |
| SCHEMBL102846 | 0.87 | HPGDS (0.43) | MMP1MMP9KMT2ARAB9AMAPT | |
| SCHEMBL25666240 | 0.85 | MMP1 (0.38) | MMP1MMP2MMP9MMP12HPGDS | |
| SCHEMBL25666205 | 0.82 | MMP1 (0.42) | MMP1MMP2MMP9MMP12KMT2A | |
| SCHEMBL20285585 | 0.79 | HPGDS (0.44) | HPGDSPTPN1 | |
| SCHEMBL25666155 | 0.79 | ADRB2 (0.47) | — | |
| SCHEMBL25666134 | 0.79 | ADRB2 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023077678-A1 | SMALL MOLECULE COMPOUND TARGETING SRSF6 PROTEIN AND PREPARATION METHOD THEREFOR AND USE THEREOF | 中国药科大学 | 2023-05-11 | — | — | WO | disclosed |