Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 14/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 4/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 4/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 3/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30762119 | 0.79 | CACNA1H (0.40) | CACNA1HCACNA1CCACNA1BCACNA1G | |
| SCHEMBL23301651 | 0.79 | ALDH1A1 (0.36) | CACNA1HCACNA1CCACNA1BCACNA1GTRPV1 | |
| SCHEMBL29656689 | 0.79 | ALDH1A1 (0.36) | CACNA1HCACNA1CCACNA1BCACNA1GTRPV1 | |
| SCHEMBL23301157 | 0.79 | CACNA1H (0.36) | CACNA1HCACNA1CCACNA1BCACNA1G | |
| SCHEMBL21348441 | 0.75 | PARP1 (0.50) | PARP1 | |
| SCHEMBL15933661 | 0.72 | CES2 (0.41) | CACNA1HCACNA1CCACNA1BCACNA1G | |
| SCHEMBL13043830 | 0.70 | EGFR (0.49) | IRAK4 | |
| SCHEMBL29656874 | 0.68 | NOS3 (0.44) | CACNA1HCACNA1CCACNA1BCACNA1G | |
| SCHEMBL23301410 | 0.68 | NOS3 (0.37) | CACNA1HCACNA1CCACNA1BCACNA1G | |
| SCHEMBL29656845 | 0.68 | NOS3 (0.37) | CACNA1HCACNA1CCACNA1BCACNA1G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104714-A1 | PESTICIDALLY ACTIVE PYRIDAZINONE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2023-06-15 | — | — | WO | disclosed |