SCHEMBL256706

SCHEMBL256706

CC/C=C/c1cccnc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 2/20 0.62
CHRNA4 P43681 2/20 0.62
MEN1 O00255 2/20 0.62
KMT2A Q03164 2/20 0.62
CHRNB4 P30926 1/20 0.62
CHRNA3 P32297 1/20 0.62
CHRNA7 P36544 1/20 0.62
CYP2D6 P10635 1/20 0.62
CYP2C9 P11712 1/20 0.62
ALOX15 P16050 1/20 0.62
CYP2C19 P33261 1/20 0.62
CYP11B1 P15538 1/20 0.59
CYP11B2 P19099 1/20 0.59
RAB9A P51151 3/20 0.52
NPC1 O15118 2/20 0.52
MAPT P10636 2/20 0.52
KDM4E B2RXH2 1/20 0.52
JUN P05412 1/20 0.52
NFKB1 P19838 1/20 0.52
MAPK1 P28482 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29511509 1.00 CHRNB2 (0.62) CHRNB2CHRNA4MEN1KMT2ACHRNB4
SCHEMBL2305391 1.00 CHRNB2 (0.62) CHRNB2CHRNA4MEN1KMT2ACHRNB4
SCHEMBL22714727 1.00 CHRNB2 (0.62) CHRNB2CHRNA4MEN1KMT2ACHRNB4
SCHEMBL22562673 0.87 CYP11B1 (0.53) CHRNB2CHRNA4MEN1KMT2ACHRNB4
SCHEMBL6952871 0.85 CHRNB2 (0.68) CHRNB2CHRNA4MEN1KMT2ACHRNB4
SCHEMBL6956730 0.85 CHRNB2 (0.68) CHRNB2CHRNA4MEN1KMT2ACHRNB4
SCHEMBL2305112 0.85 CHRNB2 (0.68) CHRNB2CHRNA4MEN1KMT2ACHRNB4
SCHEMBL6966605 0.82 CHRNB2 (0.64) CHRNB2CHRNA4MEN1KMT2ACHRNB4
SCHEMBL7520275 0.82 CHRNB2 (0.64) CHRNB2CHRNA4MEN1KMT2ACHRNB4
SCHEMBL2302782 0.82 CHRNB2 (0.64) CHRNB2CHRNA4MEN1KMT2ACHRNB4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260068882-A1 ARTHROPOD CONTROLLING COMPOSITION FIRMENICH & CIE (CH) 2026-03-12 US claimed
US-20220142158-A1 ARTHROPOD CONTROL COMPOSITIONS FIRMENICH SA (CH) 2022-05-12 US claimed
EP-3930461-A1 ARTHROPOD CONTROLLING COMPOSITION Firmenich SA (CH) 2022-01-05 EP claimed
EP-3930460-A1 ARTHROPOD CONTROL COMPOSITIONS Firmenich SA (CH) 2022-01-05 EP claimed
WO-2020239980-A1 ARTHROPOD CONTROLLING COMPOSITION FIRMENICH SA (CH) 2020-12-03 WO claimed
WO-2020239954-A1 ARTHROPOD CONTROL COMPOSITIONS FIRMENICH SA (CH) 2020-12-03 WO claimed
US-20260068882-A1 ARTHROPOD CONTROLLING COMPOSITION FIRMENICH & CIE (CH) 2026-03-12 US disclosed
US-12290611-B2 Cell or tissue embedding device JAPAN VAM & POVAL CO., LTD. (JP) 2025-05-06 US disclosed
US-20250118863-A1 COMPOSITION CONTAINING INORGANIC-ORGANIC HYBRID COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-04-10 US disclosed
EP-4458900-A1 COMPOSITION CONTAINING INORGANIC/ORGANIC HYBRID COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-11-06 EP disclosed
EP-3586824-B1 CELL- OR TISSUE-EMBEDDING DEVICE JAPAN VAM & POVAL CO LTD (JP) 2024-09-04 EP disclosed
CN-118265752-A Composition containing inorganic/organic hybrid compound 信越化学工业株式会社 2024-06-28 CN disclosed
US-20240100227-A1 IMPLANTATION DEVICE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-03-28 US disclosed
US-20090209547-A1 C-8 HALOGENATED MACROLIDES ENANTA PHARMACEUTICALS, INC. 2009-08-20 US disclosed
US-7169786-B2 Isoxazoline derivatives as anti-depressants JANSSEN-CILAG S.A. (ES) 2007-01-30 US disclosed
US-7169786-B2 Isoxazoline derivatives as anti-depressants JANSSEN-CILAG S.A. (ES) 2007-01-30 US disclosed
EP-0891331-B1 N-(2 OXOACETYL OR SULPHONYL)-PYRROLIDINE/PIPERIDINE-2-CARBOXYLIC ACID DERIVATIVES WITH IMPROVED MULTI-DRUG RESISTANCE ACTIVITY VERTEX PHARMA (US) 2003-10-01 EP disclosed
EP-0973743-A1 PHARMACEUTICAL COMPOSITIONS INCORPORATING ARYL SUBSTITUTED OLEFINIC AMINE COMPOUNDS R.J. REYNOLDS TOBACCO COMPANY (US) 2000-01-26 EP disclosed
US-5811442-A ADMINISTERING ARYL SUBSTITUTED OLEFINIC AMINE COMPOUND IN AN AMOUNT SUFFICIENT TO SELECTIVELY BIND TO AND AFFECT NICOTINIC CHOLINERGIC RECEPTOR SUBTYPES CONTAINING BETA2 SUBUNITS TARGACEPT, INC. 1998-09-22 US disclosed
WO-1998037071-A1 PHARMACEUTICAL COMPOSITIONS INCORPORATING ARYL SUBSTITUTED OLEFINIC AMINE COMPOUNDS R.J. REYNOLDS TOBACCO COMPANY (US) 1998-08-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260068882-A1 ARTHROPOD CONTROLLING COMPOSITION CNOT9, MSL1, MT-CO2 CHRNB2 478/4885CHRNA4 394/4885MEN1 1930/4885
US-20090209547-A1 C-8 HALOGENATED MACROLIDES CYP2C8, CCR8, CXCL8 CHRNB2 4739/4885CHRNA4 4732/4885MEN1 3130/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.