SCHEMBL25670909

SCHEMBL25670909

CC(C)(c1cccc(C(C)(C)C2C=C(Cl)C(N)=CC2)c1)c1ccc(N)c(Cl)c1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.33
ESR2 Q92731 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22280537 0.78 ESR2 (0.50) ESR1ESR2
SCHEMBL25671352 0.72 ESR2 (0.49) ESR1ESR2
SCHEMBL2811051 0.71 TSHR (0.50) ESR1ESR2
SCHEMBL11019379 0.70 CNR1 (0.47) ESR1ESR2
SCHEMBL22280536 0.70 CYP3A4 (0.48) ESR1ESR2
SCHEMBL10447989 0.62 ESR1 (0.53) ESR1ESR2
SCHEMBL2963375 0.62 ALDH1A1 (0.52) ESR2
SCHEMBL30279249 0.62 ALDH1A1 (0.52) ESR2
SCHEMBL9612031 0.60 TSHR (0.48) ESR2
SCHEMBL4467655 0.60 ESR1 (0.60) ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3583150-B1 GLYCIDYL AMINE EPOXY RESINS BASED ON AMES NEGATIVE AMINES ADITYA BIRLA CHEMICALS THAILAND LTD (TH) 2023-06-07 EP disclosed